CFA77_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CFA77_HUMAN
• UniProt AC: Q6ZQR2
• Protein Name: Cilia- and flagella-associated protein 77 {ECO:0000305}
• Gene Name: CFAP77 {ECO:0000312|HGNC:HGNC:33776}
• Organism: Homo sapiens (Human).
• Sequence Length: 320
• Subcellular Localization: Cell projection, cilium .
• Protein Sequence: MPEARSSGPDLTRWRKQQQPVRRTVSQVCPPPRRPLTVADIRSGMENERLGVVRDSMFQNPLIVKAAGPASVGTSYSVYDSSAVQKVIPSLAGHHIKGGPQAELGKPRERSYSLPGINFNYGLYIRGLDGGVPEAIGRWNVFKQQPTCPHELTRNYIAMNRGAVKAGLVTARENLLYRQLNDIRISDQDDRRMKKEPPPLPPNMTFGIRARPSTPFFDLLQHRYLQLWVQEQKATQKAIKLEKKQKVVLGKLYETRSSQLRKYKPPVKLDTLWHMPHFQKVGRHLDTFPTEADRQRALKAHREECAVRQGTLRMGNYTHP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MPEARSSGPDLTR --CCCHHHCCCCHHH		29255136
7	Phosphorylation	-MPEARSSGPDLTRW -CCCHHHCCCCHHHH		29255136
24	Phosphorylation	QQQPVRRTVSQVCPP HCCCCCCHHHHCCCC		23312004
26	Phosphorylation	QPVRRTVSQVCPPPR CCCCCHHHHCCCCCC		23312004
37	Phosphorylation	PPPRRPLTVADIRSG CCCCCCCCHHHHHHC		21406692
43	Phosphorylation	LTVADIRSGMENERL CCHHHHHHCCCCCCC		29209046
76	Phosphorylation	PASVGTSYSVYDSSA CCCCCCCEEECCHHH		24247654
77	Phosphorylation	ASVGTSYSVYDSSAV CCCCCCEEECCHHHH		24247654
121	Phosphorylation	LPGINFNYGLYIRGL CCCCEECCEEEEECC		-
124	Phosphorylation	INFNYGLYIRGLDGG CEECCEEEEECCCCC		-
194	Acetylation	DQDDRRMKKEPPPLP CHHHHHHHCCCCCCC		12435459
205	Phosphorylation	PPLPPNMTFGIRARP CCCCCCCEEEEECCC		-
213	Phosphorylation	FGIRARPSTPFFDLL EEEECCCCCCHHHHH		27966365
214	Phosphorylation	GIRARPSTPFFDLLQ EEECCCCCCHHHHHH		30622161
237	Acetylation	QEQKATQKAIKLEKK HHHHHHHHHHHHHHH		7695335
240	Acetylation	KATQKAIKLEKKQKV HHHHHHHHHHHHHHH		7695343
246	Acetylation	IKLEKKQKVVLGKLY HHHHHHHHHHEHHCC		7491995
253	Phosphorylation	KVVLGKLYETRSSQL HHHEHHCCHHHHHHH		-
263	Phosphorylation	RSSQLRKYKPPVKLD HHHHHHHCCCCCCCH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CFA77_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CFA77_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CFA77_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TBA3C_HUMAN	TUBA3C	physical	26186194
TBA3C_HUMAN	TUBA3C	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.