dbPTM

CDPKX_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDPKX_ARATH
UniProt AC	Q9C6P3
Protein Name	Calcium-dependent protein kinase 33 {ECO:0000303\|PubMed:12068094, ECO:0000303\|PubMed:12805596, ECO:0000303\|Ref.5}
Gene Name	CPK33 {ECO:0000303\|PubMed:12068094, ECO:0000303\|PubMed:12805596, ECO:0000303\|Ref.5}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	521
Subcellular Localization	Cell membrane Lipid-anchor . Nucleus . Cytoplasm .
Protein Description	Ca(2+)-dependent protein kinase. [PubMed: 26662273 Negative regulator of stomatal closure and slow anion currents]
Protein Sequence	MGNCLAKKYGLVMKPQQNGERSVEIENRRRSTHQDPSKISTGTNQPPPWRNPAKHSGAAAILEKPYEDVKLFYTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYKDIVGSAYYVAPEVLKRRYGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKVIAENIDTEEIQGLKAMFANIDTDNSGTITYEELKEGLAKLGSRLTEAEVKQLMDAADVDGNGSIDYIEFITATMHRHRLESNENVYKAFQHFDKDGSGYITTDELEAALKEYGMGDDATIKEILSDVDADNDGRINYDEFCAMMRSGNPQQPRLF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNCLAKKY ------CCCHHHHHH	33.29	-
56	Phosphorylation	WRNPAKHSGAAAILE CCCCCCCCCCEEHHC	29.44	30291188
237	Phosphorylation	VYKDIVGSAYYVAPE EEECCCCHHHEECHH	11.38	19880383
239	Phosphorylation	KDIVGSAYYVAPEVL ECCCCHHHEECHHHH	10.52	19880383
491	Phosphorylation	ATIKEILSDVDADND CCHHHHHHCCCCCCC	41.05	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDPKX_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDPKX_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDPKX_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
FD_ARATH	FD	physical	25661797

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDPKX_ARATH

Related Literatures of Post-Translational Modification