dbPTM

CDAC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDAC1_HUMAN
UniProt AC	Q9BWV3
Protein Name	Cytidine and dCMP deaminase domain-containing protein 1
Gene Name	CDADC1
Organism	Homo sapiens (Human).
Sequence Length	514
Subcellular Localization
Protein Description	May play an important role in testicular development and spermatogenesis..
Protein Sequence	MKEAGQMQNLESARAGRSVSTQTGSMTGQIPRLSKVNLFTLLSLWMELFPAEAQRQKSQKNEEGKHGPLGDNEERTRVSTDKRQVKRTGLVVVKNMKIVGLHCSSEDLHAGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASSSEDAKLDAKAVERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKITKTLPDANTDFYYECKQERIKEYEMLFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLILLLATVASSVPNFKHFGFYRSNPEQINEIHNQSLPQEIARHCMVQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFVGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIIHAEQNALTFRCQEIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGELEGVSKFTWQLNPSGAYGLEQNEPERRENGVLRPVPQKEEQHQDKKLRLGIH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	Phosphorylation	LGDNEERTRVSTDKR CCCHHHCCCCCCCHH	38.41	29514088
79	Phosphorylation	NEERTRVSTDKRQVK HHHCCCCCCCHHHCC	27.83	29514088
80	Phosphorylation	EERTRVSTDKRQVKR HHCCCCCCCHHHCCC	42.56	29514088
104	Phosphorylation	KIVGLHCSSEDLHAG EEEEEEECCCCCCCC	26.47	22210691
105	Phosphorylation	IVGLHCSSEDLHAGQ EEEEEECCCCCCCCC	40.29	22210691
120	Phosphorylation	IALIKHGSRLKNCDL EEEEECCCCCCCCCE	33.87	28509920
128	Phosphorylation	RLKNCDLYFSRKPCS CCCCCCEECCCCCHH	6.05	28509920
130	Phosphorylation	KNCDLYFSRKPCSAC CCCCEECCCCCHHHH	26.32	28509920
288	Phosphorylation	LLLATVASSVPNFKH HHHHHHHHCCCCCCC	27.77	-
289	Phosphorylation	LLATVASSVPNFKHF HHHHHHHCCCCCCCC	31.68	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDAC1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDAC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDAC1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
UH1BL_HUMAN	UHRF1BP1L	physical	27173435

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDAC1_HUMAN

Related Literatures of Post-Translational Modification