dbPTM

CD53_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CD53_HUMAN
UniProt AC	P19397
Protein Name	Leukocyte surface antigen CD53
Gene Name	CD53
Organism	Homo sapiens (Human).
Sequence Length	219
Subcellular Localization	Cell membrane. Cell junction. Membrane Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes..
Protein Description	Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity)..
Protein Sequence	MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQTIGL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
116	Ubiquitination	KLNEYVAKGLTDSIH HHHHHHHCCCCHHHH	44.39	-
129	N-linked_Glycosylation	IHRYHSDNSTKAAWD HHHHCCCCCCHHHHH	55.37	UniProtKB CARBOHYD
148	N-linked_Glycosylation	FLQCCGINGTSDWTS HHHHHCCCCCCCCCC	32.73	UniProtKB CARBOHYD
166	Ubiquitination	ASCPSDRKVEGCYAK CCCCCCCCCCCCHHH	50.02	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CD53_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CD53_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CD53_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KPCA_HUMAN	PRKCA	physical	11325968
GGT1_HUMAN	GGT1	physical	9862348
CD81_HUMAN	CD81	physical	9862348
CD82_HUMAN	CD82	physical	9862348

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CD53_HUMAN

Related Literatures of Post-Translational Modification