CCNG1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCNG1_MOUSE
• UniProt AC: P51945
• Protein Name: Cyclin-G1
• Gene Name: Ccng1
• Organism: Mus musculus (Mouse).
• Sequence Length: 294
• Subcellular Localization: Nucleus .
• Protein Description: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation..
• Protein Sequence: MIEVLTTDSQKLLHQLNTLLEQESRCQPKVCGLKLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKATEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLVHDTLPFERRNDLNFERLEAQLKACHCRIIFSKAKPSVLALSILALEIQALKYVELTEGVECIQKHSKISGRDLTFWQELVSKCLTEYSSNKCSKPNGQKLKWIVSGRTARQLKHSYYRITHLPTIPETIC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
269	Phosphorylation	QKLKWIVSGRTARQL CEEEEEEECCCHHHH	17.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCNG1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCNG1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCNG1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
2A5A_HUMAN	PPP2R5A	physical	11983168
PP2AA_HUMAN	PPP2CA	physical	11983168
2AAA_HUMAN	PPP2R1A	physical	11983168
MDM2_MOUSE	Mdm2	physical	11983168

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.