| UniProt ID | CCNA1_MOUSE | |
|---|---|---|
| UniProt AC | Q61456 | |
| Protein Name | Cyclin-A1 | |
| Gene Name | Ccna1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 421 | |
| Subcellular Localization | Nucleus. Cytoplasm, cytoskeleton, spindle. In oocytes at least, it associates with the spindle during metaphase. | |
| Protein Description | May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.. | |
| Protein Sequence | MHRQSSKSGVALPPVGQGPDACQMLSRAQLGQDPPQRTVLGVLTENEQYRRTCGQEITAIRCFSGSENVFPAAGKKVLSDHGVNEPAKRGFDIYMDDPEQGDRDTCSGKEGIIFEDVYEVDTSMLKSDLHFLLDFNTVSPMLVDPTTHAQSEEATDFGSDVINVTEYAEEIHRYLREAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRTETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAILLASKYEEIYPPDVDEFVYITDDTYTKRQLLRMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCIRTENLAKYVAELSLLEADPFLKYLPSLVAAAAYCLANYIVNRHFWPETLAAFTGYSLNEIVPCLSELHKACLSIPHRPQQAIREKYKASKYLHVSLMEPPVVLPLQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 247 | Phosphorylation | GKLQLVGTAAILLAS HHHHHHHHHHHHHHH | 12.87 | - | |
| 254 | Phosphorylation | TAAILLASKYEEIYP HHHHHHHHCCCCCCC | 35.42 | - | |
| 256 | Phosphorylation | AILLASKYEEIYPPD HHHHHHCCCCCCCCC | 19.12 | 22871156 | |
| 274 | Phosphorylation | FVYITDDTYTKRQLL CEEECCCCCCHHHHH | 35.58 | 22871156 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CCNA1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CCNA1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CCNA1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CDN1A_MOUSE | Cdkn1a | physical | 14966563 | |
| CDK2_MOUSE | Cdk2 | physical | 15707957 | |
| CDK2_MOUSE | Cdk2 | physical | 12121977 | |
| CDK2_MOUSE | Cdk2 | physical | 15155733 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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