CCG1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCG1_HUMAN
• UniProt AC: Q06432
• Protein Name: Voltage-dependent calcium channel gamma-1 subunit
• Gene Name: CACNG1
• Organism: Homo sapiens (Human).
• Sequence Length: 222
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex..
• Protein Sequence: MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	N-linked_Glycosylation	SPHMEHHNTTCEAAH CCCCHHCCCHHHHHH	38.70	UniProtKB CARBOHYD
79	N-linked_Glycosylation	ITLPGEKNCSYFRHF EECCCCCCCCCCCCC	18.70	UniProtKB CARBOHYD
135	Phosphorylation	SLGKKRDYLLRPASM HCCCCCCCCCCHHHH	16.21	-
161	Phosphorylation	SVEVMRQSVKRMIDS HHHHHHHHHHHHCCC	21.17	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCG1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCG1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCG1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VAPA_HUMAN	VAPA	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.