CC150_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC150_HUMAN
• UniProt AC: Q8NCX0
• Protein Name: Coiled-coil domain-containing protein 150
• Gene Name: CCDC150
• Organism: Homo sapiens (Human).
• Sequence Length: 1101
• Protein Sequence: MDCKVHMETTVSRPVLSPTHINATASETFTVLQQRMRIVEEQTSSLRDDLIMLDFGEKRGYLEAPDCLEDLDSQKVISPIQNEAICAGKTDILWKNCEFLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYLRSEIMSLHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAILQVEQKMMTQTFQEQNLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLESKELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRNKQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEEAHRWFKHRFDGLQLELTKNRLQRPSGEDRWQEKDQDVKHDVMSNQSVLHRWERKQNLRPMPKKYHSEVQRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Acetylation	IMLDFGEKRGYLEAP EEEECCCCCCCCCCC	52.05	11716473
75	Acetylation	LEDLDSQKVISPIQN HHCCCCCCCCCCCCC	45.55	11716481
109 (in isoform 2)	Phosphorylation	-	33.46	29083192
112 (in isoform 2)	Phosphorylation	-	51.40	29083192
189	Phosphorylation	TATLKIASQTKKNAA HHHHHHHHHCHHHHH	41.68	-
191	Phosphorylation	TLKIASQTKKNAAII HHHHHHHCHHHHHHH	41.30	-
212	Methylation	TKRKMNLKIQELRRQ HHHHHHHHHHHHHHH	37.02	23644510
290	Phosphorylation	KEELEIATSQLKSDL HHHHHHHHHHHHHCC	23.75	29457462
291	Phosphorylation	EELEIATSQLKSDLT HHHHHHHHHHHHCCC	25.21	29457462
469	Phosphorylation	ASMQEKKSLLEEKER HHHHHHHHHHHHHHH	49.61	24719451
625	Phosphorylation	AHLKEVKSILERSKE HHHHHHHHHHHHCHH	37.27	23312004
630	Phosphorylation	VKSILERSKEELSRT HHHHHHHCHHHHHHH	34.74	25954137
693	Phosphorylation	MLENVLASHSKMQGA EHHHHHHHCHHHHHH	24.92	25690035
781	Phosphorylation	SLEQALQTNNHLQTK HHHHHHHHCCCHHHH	38.55	29396449
787	Phosphorylation	QTNNHLQTKLDHIQE HHCCCHHHHHHHHHH	39.68	29396449
864	Phosphorylation	LDEANFRSVEVSRTN HHHCCCCHHHHHHHH	20.63	26074081
868	Phosphorylation	NFRSVEVSRTNRELR CCCHHHHHHHHHHHH	21.63	26074081
870	Phosphorylation	RSVEVSRTNRELRQK CHHHHHHHHHHHHHH	30.99	26074081
887	Phosphorylation	ELEKILESNKEKIKN HHHHHHHHCHHHHHC	50.16	24425749
933	Phosphorylation	MELIKDQYQKKNYEQ HHHHHHHHHHCCHHH	32.22	30622161
943	Phosphorylation	KNYEQSLSIQRFVCE CCHHHHHHHHHHHHH	23.17	24719451
984	Ubiquitination	LHLEAERKIRQELEN HHHHHHHHHHHHHHH	33.47	-
1094	Phosphorylation	LRPMPKKYHSEVQRK CCCCCHHHHHHHHCC	19.39	30108239
1096	Phosphorylation	PMPKKYHSEVQRK-- CCCHHHHHHHHCC--	36.05	30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC150_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC150_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC150_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CF161_HUMAN	C15orf26	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.