CC149_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC149_HUMAN
• UniProt AC: Q6ZUS6
• Protein Name: Coiled-coil domain-containing protein 149
• Gene Name: CCDC149
• Organism: Homo sapiens (Human).
• Sequence Length: 474
• Protein Sequence: MANQLRERHQSLKKKYRELIDGDPSLPPEKRKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNKLLRMTIAKQRLGDEAIGVRHFAAHEREDLVQQLERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERLNQELNHILSGHENRIIDVDALCMENRYLQERLKQLHEEVNLLKSNIAKYKNALERRKNSKGQGKSSSSALTGVLSAKQVQDLLSEDHGCSLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNKILGNRVAELEKKLRTLEVSGLWSLPGGKDTILFSDPTLPSGQRSRSPLLKFVEQPTENKADPKDGEAQKQEEDESCAAAEALTAPEDAGRPAVNSPANQSRGNQCKLFHPSLPQLPSEEEVNSLGREIIKLTKEQAAAELEEVRRESPIEGQRSETGPAPPGLAIQGELPKSHLDSFEASRPAAKASTPEDGKGIPEGGGMRSTVKT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	HQSLKKKYRELIDGD HHHHHHHHHHHHCCC	20.42	18083107
74	Phosphorylation	DNKLLRMTIAKQRLG CHHHHHHHHHHHHHC	16.02	24719451
149	Phosphorylation	QELNHILSGHENRII HHHHHHHCCCCCCEE	37.18	24719451
215	Phosphorylation	SALTGVLSAKQVQDL HHHHHHHCHHHHHHH	30.89	28348404
270	Phosphorylation	RQTNKILGNRVAELE HHHCHHHHHHHHHHH	24.30	27251275
282	Phosphorylation	ELEKKLRTLEVSGLW HHHHHHCCEEECCCC	37.39	20873877
286	Phosphorylation	KLRTLEVSGLWSLPG HHCCEEECCCCCCCC	20.84	20873877
290	Phosphorylation	LEVSGLWSLPGGKDT EEECCCCCCCCCCCE	29.72	20873877
304	Phosphorylation	TILFSDPTLPSGQRS EEEECCCCCCCCCCC	57.18	29514088
307	Phosphorylation	FSDPTLPSGQRSRSP ECCCCCCCCCCCCCC	51.15	29514088
311	Phosphorylation	TLPSGQRSRSPLLKF CCCCCCCCCCCHHHH	29.26	26699800
313	Phosphorylation	PSGQRSRSPLLKFVE CCCCCCCCCHHHHHC	22.58	29514088
366	Phosphorylation	AVNSPANQSRGNQCK CCCCCCCCCCCCCCC	36.29	-
368	Phosphorylation	NSPANQSRGNQCKLF CCCCCCCCCCCCCCC	38.01	24719451
378	Phosphorylation	QCKLFHPSLPQLPSE CCCCCCCCCCCCCCH	44.08	27251275
384	Phosphorylation	PSLPQLPSEEEVNSL CCCCCCCCHHHHHHH	67.25	26657352
399	Phosphorylation	GREIIKLTKEQAAAE HHHHHHHHHHHHHHH	27.77	-
414	Phosphorylation	LEEVRRESPIEGQRS HHHHHHHCCCCCCCC	29.39	25849741
433	Phosphorylation	APPGLAIQGELPKSH CCCCCEEECCCCHHH	33.43	-
439	Phosphorylation	IQGELPKSHLDSFEA EECCCCHHHHHHHHH	27.61	24719451
447	Phosphorylation	HLDSFEASRPAAKAS HHHHHHHCCCHHHCC	31.44	24719451
455	Phosphorylation	RPAAKASTPEDGKGI CCHHHCCCCCCCCCC	35.24	24719451
469	Phosphorylation	IPEGGGMRSTVKT-- CCCCCCCCCCCCC--	32.24	24719451
494	Phosphorylation	--------------------------- ---------------------------		24719451
502	Phosphorylation	----------------------------------- -----------------------------------		24719451
510	Phosphorylation	------------------------------------------- -------------------------------------------		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC149_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC149_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC149_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.