dbPTM

CC126_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CC126_HUMAN
UniProt AC	Q96EE4
Protein Name	Coiled-coil domain-containing protein 126
Gene Name	CCDC126
Organism	Homo sapiens (Human).
Sequence Length	140
Subcellular Localization	Secreted .
Protein Description
Protein Sequence	MFFTISRKNMSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSAANTTNGTSGNLVPVTTNKRTNVSGSIR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MFFTISRKNMS ----CCCCCCCCCHH	13.53	30622161
6	Phosphorylation	--MFFTISRKNMSQK --CCCCCCCCCHHHH	33.86	30622161
11	Phosphorylation	TISRKNMSQKLSLLL CCCCCCHHHHHHHHH	33.29	30622161
54	Ubiquitination	EQILDLSKRYVKALA HHHHHHHHHHHHHHH	55.86	-
54	2-Hydroxyisobutyrylation	EQILDLSKRYVKALA HHHHHHHHHHHHHHH	55.86	-
75	Phosphorylation	VDVENGASMAGYADL EECCCCCCCCHHHHH	15.57	24961811
79	Phosphorylation	NGASMAGYADLKRTI CCCCCCHHHHHHHHH	6.34	24961811
85	Phosphorylation	GYADLKRTIAVLLDD HHHHHHHHHHHHHHH	16.23	22210691
85	O-linked_Glycosylation	GYADLKRTIAVLLDD HHHHHHHHHHHHHHH	16.23	OGP
110	N-linked_Glycosylation	KVDYIVVNGSAANTT CCCEEEECCCCCCCC	28.01	UniProtKB CARBOHYD
133	Phosphorylation	PVTTNKRTNVSGSIR ECCCCCCCCCCCCCC	41.40	29496963
134	N-linked_Glycosylation	VTTNKRTNVSGSIR- CCCCCCCCCCCCCC-	29.95	UniProtKB CARBOHYD
136	Phosphorylation	TNKRTNVSGSIR--- CCCCCCCCCCCC---	28.97	28270605
138	Phosphorylation	KRTNVSGSIR----- CCCCCCCCCC-----	14.00	29496963

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CC126_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CC126_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CC126_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
HD_HUMAN	HTT	physical	23275563

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CC126_HUMAN

Related Literatures of Post-Translational Modification