C1QT3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: C1QT3_HUMAN
• UniProt AC: Q9BXJ4
• Protein Name: Complement C1q tumor necrosis factor-related protein 3
• Gene Name: C1QTNF3
• Organism: Homo sapiens (Human).
• Sequence Length: 246
• Subcellular Localization: Secreted .
• Protein Sequence: MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70 (in isoform 3)	N-linked_Glycosylation	-	45.76	-
89	Acetylation	AKGEKGDKGDLGPRG CCCCCCCCCCCCCCC	64.09	7669935
104	Acetylation	ERGQHGPKGEKGYPG CCCCCCCCCCCCCCC	81.78	7669943
179	Phosphorylation	HEDVEEVYVYLMHNG CCCHHEEEEEEEECC	6.15	-
205	Phosphorylation	KGKSDTSSNHAVLKL CCCCCCCCCCEEEHH	34.43	28787133

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of C1QT3_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
70	N	Glycosylation	[Isoform 3]: Glycosylated on Asn-70.	19139490

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of C1QT3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GT252_HUMAN	COLGALT2	physical	26186194
GT252_HUMAN	COLGALT2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.