BRNP1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BRNP1_MOUSE
• UniProt AC: Q920P3
• Protein Name: BMP/retinoic acid-inducible neural-specific protein 1
• Gene Name: Brinp1
• Organism: Mus musculus (Mouse).
• Sequence Length: 760
• Subcellular Localization: Cytoplasm.
• Protein Description: Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway..
• Protein Sequence: MNWRFVELLYFLFVWGRISVQPSRQEPAGTDQHVSKEFDWLISDRGPFHHSRSYLSFVERHRQGFTTRYKIYREFARWKVRNTAIERRDLVRHPVPLMPEFQRSIRLLGRRPTTQQFIDTIIKKYGTHLLISATLGGEEALTMYMDKSRLDRKSGNATQSVEALHQLASSYFVDRDGTMRRLHEIQISTGAIKVTETRTGPLGCNSYDNLDSVSSVLLQSTESKLHLQGLQIIFPQYLQEKFVQSALSYIMCNGEGEYVCQNSQCRCQCAEEFPQCNCPITDIQIMEFTLANMAKAWTEAYKDLENSDEFKSFMKRLPSNHFLTIGSIHQHWGNDWDLQSRYKLLQSATEAQRQKIQRTARKLFGLSVRCRHNPNHQLPRERTIQQWLARVQSLLYCNENGFWGTFLESQRSCVCHGSTTLCQRPIPCIIGGNNSCAMCSLANISLCGSCNKGYKLYRGRCEPQNVDSERSEQFISFETDLDFQDLELKYLLQKMDSRLYVHTTFISNEIRLDTFFDPRWRKRMSLTLKSNKNRMDFIHMVIGMSMRICQMRNSSLDPMFFVYVNPFSGSHSEGWNMPFGEFGYPRWEKIRLQNSQCYNWTLLLGNRWKTFFETVHIYLRSRTRLPTLRNETGQGPVDLSDPSKRQFYIKISDVQVFGYSLRFNADLLRSAVQQVNQSYTQGGQFYSSSSVMLLMLDIRDRINRLAPPVAPGKPQLDLFSCMLKHRLKLTNSEIIRVNHALDLYNTEILKQSDQMTAKLC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
156	N-linked_Glycosylation	RLDRKSGNATQSVEA HCCCCCCCHHHHHHH		-
433	N-linked_Glycosylation	IPCIIGGNNSCAMCS CCEEECCCCCCHHHH		-
443	N-linked_Glycosylation	CAMCSLANISLCGSC CHHHHCCCEEECCCC		-
553	N-linked_Glycosylation	MRICQMRNSSLDPMF HHHHHHCCCCCCCEE		-
599	N-linked_Glycosylation	LQNSQCYNWTLLLGN ECCCCEECEEEEECC		-
630	N-linked_Glycosylation	TRLPTLRNETGQGPV CCCCCCCCCCCCCCC		-
676	N-linked_Glycosylation	RSAVQQVNQSYTQGG HHHHHHHHHHHHCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BRNP1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BRNP1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BRNP1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P53_MOUSE	Trp53	physical	25732823

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.