BON1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BON1_ARATH
• UniProt AC: Q941L3
• Protein Name: Protein BONZAI 1
• Gene Name: BON1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 578
• Subcellular Localization: Cell membrane ; Lipid-anchor . Calcium enhances the association with membranes.
• Protein Description: Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties..
• Protein Sequence: MGNCCSDVASGAGATAGVGGSGSSAALGATNDALDYYLKSKGFNGLFSQIELSFSASNLRDRDVLSKSDPMVVVYQKEKDATLSEVFRSEVVLNSLAPKWIKKFIVAYHFETVQTLVFRVYDVDTKFQNSREEMLKLDEQQFLGEATCALSEIITKSTRTSTLELKRKDGFAPQAQPHHGKLIIHAEESLASKISTEIVFRCSNLESKDLFSKSDPFLVVSKIVEHGTPIPVSKTEVRKNDLNPIWKPVFLSVQQVGSKDSPVIIECSDFNSNGKHSLIGKVQKSLSDLEKLHLAGQGINFSLPTGAGQNKVLKSQLFVDKFTETVHHTFLEYLASGFELNFMVAIDFTASNGNPRLPDSLHYIDPSGRLNAYQRAIMDVGEVLQFYDSDKRFPAWGFGARPIDAPVSHCFNLNGSSSYSEVDGIQGIMTSYTSALFNVSLAGPTLFGPVINAAAMIASASLAQGSRKYYVLLIITDGVITDLQETKDALVSASDLPLSILIVGVGGADFKEMEILDADKGERLESSSGRLASRDIVQFVALRDVQYGEISVVQALLAELPSQFLTYMRIRNMKPIPP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNCCSDVA ------CCCCHHHCC	35.56	20634289
6	Phosphorylation	--MGNCCSDVASGAG --CCCCHHHCCCCCC	37.00	27531888
30	Phosphorylation	SSAALGATNDALDYY HHHHHCCCHHHHHHH	31.65	27531888
40	Phosphorylation	ALDYYLKSKGFNGLF HHHHHHHHCCCCCEE	35.10	27531888
228	Phosphorylation	SKIVEHGTPIPVSKT EEHHHCCCCCCCCCC	21.69	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BON1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BON1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BON1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAP1_ARATH	BAP1	physical	20634289
BAK1_ARATH	BAK1	physical	21623975
MD37E_ARATH	HSC70-1	physical	26408532
MD37D_ARATH	AT5G02490	physical	26408532
HSP7C_ARATH	AT3G09440	physical	26408532
SGT1B_ARATH	SGT1B	physical	26408532
MD37E_ARATH	HSC70-1	genetic	26408532
HSP7C_ARATH	AT3G09440	genetic	26408532

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.