BEND2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BEND2_HUMAN
• UniProt AC: Q8NDZ0
• Protein Name: BEN domain-containing protein 2
• Gene Name: BEND2
• Organism: Homo sapiens (Human).
• Sequence Length: 799
• Protein Sequence: MSERTQEQDFVIITVDDSDDNNDCSIEMVEVSETADNSTNDIADDSTYVTADNPTDDTATQPNFPGGNDGHHRPLQMSYGSGSVTQAGVQWHDHSSLQPQPLGLKQFFHLSLPSSWDDRRTPPCPVAHGDQIVSQINHPVHLRRYSYNSEEVDFPKRGRFYTPEVQSSISPPAERQETHAWASPAVTSLESAACHELQEADLSESLSYPRIVSSSSLQQYVAQGGSFPCFGMPWNFISGGAESTNAVISFANATTAVPMAVLSRRESSLANNPGVVNYSALPENENVGPGRALSSFCFHPNLEMPERPANSSKNSTETANYPTLMGNYNGQNTASLSVFIPPYFAEKIILTEMPGTTETNVENNSQTVYYPALSGNTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVDTNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDSQSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQPMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGNLKHGLCALDPNKISALREFLQENYPICDLSENGRDWKSCVTSINSGIRSLRHDVRRAEARSQSLPAVTPPELEQESKPGDPDATDPST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
263	Phosphorylation	AVPMAVLSRRESSLA CCCHHHHCCCHHHHC	23.77	-
311	Phosphorylation	MPERPANSSKNSTET CCCCCCCCCCCCCCC	44.81	-
312	Phosphorylation	PERPANSSKNSTETA CCCCCCCCCCCCCCC	35.35	-
447	Phosphorylation	VDTNTENSVNTMNRS ECCCCCCCCCCCCCC	15.54	-
450	Phosphorylation	NTENSVNTMNRSTLL CCCCCCCCCCCCCCC	17.42	-
515	Phosphorylation	YLVRILFSKEILISS HHHHHHHCCCEEECC	26.40	24719451
591	Acetylation	PKTVRKNKKRTNRVA CHHHHHCCCCCCCCC	46.82	12432599
592	Acetylation	KTVRKNKKRTNRVAS HHHHHCCCCCCCCCC	74.07	12432607
626	Phosphorylation	MFQPMNNSKMREKRN CCCCCCCHHHHHHHC	23.87	28270605

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BEND2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BEND2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BEND2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.