B4GT6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: B4GT6_HUMAN
• UniProt AC: Q9UBX8
• Protein Name: Beta-1,4-galactosyltransferase 6
• Gene Name: B4GALT6
• Organism: Homo sapiens (Human).
• Sequence Length: 382
• Subcellular Localization: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.
• Protein Description: Required for the biosynthesis of glycosphingolipids..
• Protein Sequence: MSVLRRMMRVSNRSLLAFIFFFSLSSSCLYFIYVAPGIANTYLFMVQARGIMLRENVKTIGHMIRLYTNKNSTLNGTDYPEGNNSSDYLVQTTTYLPENFTYSPYLPCPEKLPYMRGFLNVNVSEVSFDEIHQLFSKDLDIEPGGHWRPKDCKPRWKVAVLIPFRNRHEHLPIFFLHLIPMLQKQRLEFAFYVIEQTGTQPFNRAMLFNVGFKEAMKDSVWDCVIFHDVDHLPENDRNYYGCGEMPRHFAAKLDKYMYILPYKEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVHYAGYNVTRPEGDLGKYKSIPHHHRGEVQFLGRYKLLRYSKERQYIDGLNNLIYRPKILVDRLYTNISVNLMPELAPIEDY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	N-linked_Glycosylation	IRLYTNKNSTLNGTD HHHHCCCCCCCCCCC	42.15	UniProtKB CARBOHYD
75	N-linked_Glycosylation	TNKNSTLNGTDYPEG CCCCCCCCCCCCCCC	51.94	UniProtKB CARBOHYD
83	N-linked_Glycosylation	GTDYPEGNNSSDYLV CCCCCCCCCCCCEEE	43.48	UniProtKB CARBOHYD
84	N-linked_Glycosylation	TDYPEGNNSSDYLVQ CCCCCCCCCCCEEEE	54.47	UniProtKB CARBOHYD
99	N-linked_Glycosylation	TTTYLPENFTYSPYL EEECCCCCCCCCCCC	32.40	UniProtKB CARBOHYD
101	O-linked_Glycosylation	TYLPENFTYSPYLPC ECCCCCCCCCCCCCC	34.37	OGP
122	N-linked_Glycosylation	MRGFLNVNVSEVSFD CCCCCCCCHHHCCHH	30.44	UniProtKB CARBOHYD
136	Phosphorylation	DEIHQLFSKDLDIEP HHHHHHHHCCCCCCC	33.58	24719451
256	Phosphorylation	FAAKLDKYMYILPYK HHHHHHHEEEEEEHH	8.53	22210691
270	Phosphorylation	KEFFGGVSGLTVEQF HHHHCCCCCCCHHHH	31.21	22210691
273	Phosphorylation	FGGVSGLTVEQFRKI HCCCCCCCHHHHHHH	26.06	22210691
307	N-linked_Glycosylation	RVHYAGYNVTRPEGD HHHHCCCCCCCCCCC	27.97	UniProtKB CARBOHYD
340	Phosphorylation	GRYKLLRYSKERQYI CHHHHHHHHHHHHHC	24.86	-
346	Phosphorylation	RYSKERQYIDGLNNL HHHHHHHHCCCHHHC	13.75	-
355	Phosphorylation	DGLNNLIYRPKILVD CCHHHCCCCCHHHHH	24.83	-
358	2-Hydroxyisobutyrylation	NNLIYRPKILVDRLY HHCCCCCHHHHHHCC	39.41	-
358	Acetylation	NNLIYRPKILVDRLY HHCCCCCHHHHHHCC	39.41	27452117
367	N-linked_Glycosylation	LVDRLYTNISVNLMP HHHHCCCCCCCCCCC	15.81	UniProtKB CARBOHYD
382	Phosphorylation	ELAPIEDY------- CCCCCCCC-------	13.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of B4GT6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of B4GT6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of B4GT6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MA2A2_HUMAN	MAN2A2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.