dbPTM

AXLP1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AXLP1_CAEEL
UniProt AC	Q3LRZ3
Protein Name	Axin-like protein 1 {ECO:0000303\|PubMed:17601533}
Gene Name	axl-1 {ECO:0000312\|EMBL:ABA28304.1}
Organism	Caenorhabditis elegans.
Sequence Length	400
Subcellular Localization
Protein Description	Works in parallel with pry-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Shown to have a role in excretory cell development..
Protein Sequence	MTMRSKFSIDRVLHDTAFAKWCQKEESRNADSITLYTSILDFESKLKTGSPSLSLLKLARHIHRKYVSLNTGTCHVIGDSIRTKISTRVHEVLDGKPPYIDLFDPLKQPLFQHLRSMHTEFSTTTADVNTTWEDASSTSSSNKGATIWFNEDAIDKSSRHEIGQSTVTHESEDDRFSFFNAVCTRLNSLQETKNSSETEEHAESPRKEKSSTPYGTDGFAPPPRSTQTNTLKVSNLPKRFESLYKKKRQQVATSDSSGFGSNASDFWSFERYGKSNQGTLERPNRLFTGTNNGFSTLQPKRRGSEAPKMTVELRYENDVPMVAKISANHAQSVTLRYFRHLFGLHYTDNCRFFFKSTCEDGSAQYQWTLLFHDDDILPVFQNRITAICRMCPPPEDHDLI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of AXLP1_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AXLP1_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AXLP1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AXLP1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GSK3_CAEEL	gsk-3	physical	17601533
GSK3B_HUMAN	GSK3B	physical	17601533

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AXLP1_CAEEL

Related Literatures of Post-Translational Modification