AXA81_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AXA81_HUMAN
• UniProt AC: Q5VT79
• Protein Name: Annexin A8-like protein 1 {ECO:0000305}
• Gene Name: ANXA8L1 {ECO:0000312|HGNC:HGNC:23334}
• Organism: Homo sapiens (Human).
• Sequence Length: 327
• Protein Sequence: MAWWKAWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	QEGVTVKSSSHFNPD HCCCEEECCCCCCCC	32.51	23090842
18	Phosphorylation	EGVTVKSSSHFNPDP CCCEEECCCCCCCCC	23.32	23090842
19	Phosphorylation	GVTVKSSSHFNPDPD CCEEECCCCCCCCCC	38.91	23090842
29	Phosphorylation	NPDPDAETLYKAMKG CCCCCHHHHHHHHHC	32.27	26356563
31	Phosphorylation	DPDAETLYKAMKGIG CCCHHHHHHHHHCCC	11.14	27259358
32	Acetylation	PDAETLYKAMKGIGT CCHHHHHHHHHCCCC	37.79	-
32	Ubiquitination	PDAETLYKAMKGIGT CCHHHHHHHHHCCCC	37.79	-
35	Ubiquitination	ETLYKAMKGIGTNEQ HHHHHHHHCCCCCHH	50.85	-
61	Ubiquitination	TQRQQIAKSFKAQFG HHHHHHHHHHHHHHC	59.04	-
74	Phosphorylation	FGKDLTETLKSELSG HCCCHHHHHHHHHCC	33.96	21082442
76	Acetylation	KDLTETLKSELSGKF CCHHHHHHHHHCCHH	49.67	-
107	Ubiquitination	KELHDAMKGLGTKEG HHHHHHHCCCCCCCC	53.34	-
161	S-palmitoylation	YLERILVCLLQGSRD HHHHHHHHHHHCCCC	2.55	29575903
184 (in isoform 2)	Phosphorylation	-	49.91	22210691
192 (in isoform 2)	Phosphorylation	-	36.46	22210691
222	Acetylation	RVFEEYEKIANKSIE HHHHHHHHHHCCCHH	46.33	-
263	Phosphorylation	SYFAERLYYAMKGAG HHHHHHHHHHHCCCC	8.73	23663014
264	Phosphorylation	YFAERLYYAMKGAGT HHHHHHHHHHCCCCC	12.57	23663014
267	Acetylation	ERLYYAMKGAGTRDG HHHHHHHCCCCCCCC	37.12	-
299	Phosphorylation	KCHFKKMYGKTLSSM HHHHHHHHCCCHHHH	25.09	18669648
304	Phosphorylation	KMYGKTLSSMIMEDT HHHCCCHHHHHHHCC	24.08	18669648
312	Phosphorylation	SMIMEDTSGDYKNAL HHHHHCCCCHHHHHH	41.82	18669648
315	Phosphorylation	MEDTSGDYKNALLSL HHCCCCHHHHHHHHH	15.07	18669648
321	Phosphorylation	DYKNALLSLVGSDP- HHHHHHHHHHCCCC-	23.12	21601212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AXA81_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AXA81_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AXA81_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RDH12_HUMAN	RDH12	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.