AUXI1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AUXI1_ARATH
• UniProt AC: Q9SU08
• Protein Name: Auxilin-related protein 1 {ECO:0000305}
• Gene Name: AUXI1 {ECO:0000305}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 904
• Subcellular Localization: Cell membrane ; Peripheral membrane protein . Golgi apparatus, trans-Golgi network . Endoplasmic reticulum . Cytoplasmic vesicle .
• Protein Description: Promotes uncoating of clathrin-coated vesicles. May interact directly with clathrin..
• Protein Sequence: MDDFTGLLARDFGLKPQGKSAPMASQSNSSAADFNTFASSYSFATAAGKKSDSLPVFDDPGRDGDDLLFKDVFSGPPPPKYGSSSGDSRSPSAPAFDYDAMFKEPKSKSASSMPVYDKPVYDDEDVFESIPELKIPSTSSQSARFENVFSSISSSPTKHRKQNSSPFDDLMGNNLGKKGADSDREEKGSSIFDDLIPGFGRTSSPPSKRTTSETTNQSEKAPYRTAETSSNVEEDPFVVLEESESTPREPSRTDPLDDIGKFNSRKTDHSSVHGGVFVDIDPLDNLGKPGPDMNSKGKSHLRPPGNISGSQSPPVESPGSYHSKKVSFEDFLEPHNMSTPPPTNSNGSFESSDDVWLTVSEIPLFTQPTSAPPPTRPPPPRPTRPIKKKVNEPSIPTSAYHSHVPSSGRASVNSPTASQMDELDDFSIGRNQTAANGYPDPSSGEDSDVFSTAAASAAAMKDAMDKAEAKFRHAKERREKENLKASRSREGDHTENYDSRERELREKQVRLDRERAEREAEMEKAQEREKEEREREQKRIERERERLVARQAVERATREARERAATEAHAKVQRAAVGKATDARERAERAAVQRAHAEARERAAAGARDKAAKAAAEAREKAEKAAAEAKERANAEAREKETRVRAERAAVERAAAEARGRAAAQAKAKQQQENTNDLDSFFSSISRPNSAPRQRTNPLDPFQDSWNKGGSFESSRESLRVPPGQPENLRKTSSVTNIVDDLSSIFGASASQSGGFQDVDGETEERRRARLERHQRTQERAAKALAEKNERDLQVQREQVEKDRIGVTLDVEIKRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTDLITAASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSEELF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
139	Phosphorylation	ELKIPSTSSQSARFE CCCCCCCCCCCHHHH	30.62	19880383
142	Phosphorylation	IPSTSSQSARFENVF CCCCCCCCHHHHHHH	24.29	30589143
150	Phosphorylation	ARFENVFSSISSSPT HHHHHHHHHHCCCCC	23.60	23776212
151	Phosphorylation	RFENVFSSISSSPTK HHHHHHHHHCCCCCC	18.28	23776212
153	Phosphorylation	ENVFSSISSSPTKHR HHHHHHHCCCCCCCC	27.06	27532006
154	Phosphorylation	NVFSSISSSPTKHRK HHHHHHCCCCCCCCC	38.37	27532006
155	Phosphorylation	VFSSISSSPTKHRKQ HHHHHCCCCCCCCCC	29.78	30291188
157	Phosphorylation	SSISSSPTKHRKQNS HHHCCCCCCCCCCCC	41.24	24601666
164	Phosphorylation	TKHRKQNSSPFDDLM CCCCCCCCCCHHHHC	36.57	23776212
165	Phosphorylation	KHRKQNSSPFDDLMG CCCCCCCCCHHHHCC	36.82	23776212
202	Phosphorylation	LIPGFGRTSSPPSKR CCCCCCCCCCCCCCC	33.66	25561503
203	Phosphorylation	IPGFGRTSSPPSKRT CCCCCCCCCCCCCCC	39.21	25561503
204	Phosphorylation	PGFGRTSSPPSKRTT CCCCCCCCCCCCCCC	39.97	25561503
207	Phosphorylation	GRTSSPPSKRTTSET CCCCCCCCCCCCCCC	37.85	25561503
243	Phosphorylation	PFVVLEESESTPREP CEEEEECCCCCCCCC	27.72	23111157
245	Phosphorylation	VVLEESESTPREPSR EEEECCCCCCCCCCC	53.65	23111157
299	Phosphorylation	DMNSKGKSHLRPPGN CCCCCCCCCCCCCCC	36.10	23776212
308	Phosphorylation	LRPPGNISGSQSPPV CCCCCCCCCCCCCCC	36.07	23776212
310	Phosphorylation	PPGNISGSQSPPVES CCCCCCCCCCCCCCC	22.24	23776212
312	Phosphorylation	GNISGSQSPPVESPG CCCCCCCCCCCCCCC	32.63	30291188
317	Phosphorylation	SQSPPVESPGSYHSK CCCCCCCCCCCCCCC	34.49	30291188
320	Phosphorylation	PPVESPGSYHSKKVS CCCCCCCCCCCCCCC	24.05	23776212
321	Phosphorylation	PVESPGSYHSKKVSF CCCCCCCCCCCCCCH	18.94	23776212
323	Phosphorylation	ESPGSYHSKKVSFED CCCCCCCCCCCCHHH	26.41	23776212
411	Phosphorylation	VPSSGRASVNSPTAS CCCCCCCCCCCCCHH	22.07	23776212
414	Phosphorylation	SGRASVNSPTASQMD CCCCCCCCCCHHHCC	22.82	30291188
416	Phosphorylation	RASVNSPTASQMDEL CCCCCCCCHHHCCCC	38.47	23776212
418	Phosphorylation	SVNSPTASQMDELDD CCCCCCHHHCCCCCC	28.63	23776212
427	Phosphorylation	MDELDDFSIGRNQTA CCCCCCCCCCCCCCC	31.00	23776212
438	Phosphorylation	NQTAANGYPDPSSGE CCCCCCCCCCCCCCC	12.31	30407730
442	Phosphorylation	ANGYPDPSSGEDSDV CCCCCCCCCCCCCHH	59.35	19880383
443	Phosphorylation	NGYPDPSSGEDSDVF CCCCCCCCCCCCHHH	52.14	19880383
447	Phosphorylation	DPSSGEDSDVFSTAA CCCCCCCCHHHHHHH	31.22	19880383
451	Phosphorylation	GEDSDVFSTAAASAA CCCCHHHHHHHHHHH	19.58	30407730
452	Phosphorylation	EDSDVFSTAAASAAA CCCHHHHHHHHHHHH	14.62	30407730
456	Phosphorylation	VFSTAAASAAAMKDA HHHHHHHHHHHHHHH	17.45	30407730
581	Phosphorylation	RAAVGKATDARERAE HHHHCHHHHHHHHHH	33.41	19880383
675	Phosphorylation	AKQQQENTNDLDSFF HHHHHHCCCCHHHHH	29.38	23776212
680	Phosphorylation	ENTNDLDSFFSSISR HCCCCHHHHHHHCCC	35.17	23776212
683	Phosphorylation	NDLDSFFSSISRPNS CCHHHHHHHCCCCCC	25.42	23776212
684	Phosphorylation	DLDSFFSSISRPNSA CHHHHHHHCCCCCCC	21.30	23776212
686	Phosphorylation	DSFFSSISRPNSAPR HHHHHHCCCCCCCCC	43.57	23776212
690	Phosphorylation	SSISRPNSAPRQRTN HHCCCCCCCCCCCCC	42.19	23776212
711	Phosphorylation	DSWNKGGSFESSRES CCCCCCCCCCCCHHH	34.21	25561503
732	Phosphorylation	QPENLRKTSSVTNIV CCHHHHCHHCCHHHH	21.57	23776212
733	Phosphorylation	PENLRKTSSVTNIVD CHHHHCHHCCHHHHH	26.33	23776212
734	Phosphorylation	ENLRKTSSVTNIVDD HHHHCHHCCHHHHHH	37.89	23776212
736	Phosphorylation	LRKTSSVTNIVDDLS HHCHHCCHHHHHHHH	22.60	23776212
743	Phosphorylation	TNIVDDLSSIFGASA HHHHHHHHHHHCCCC	28.51	23776212
744	Phosphorylation	NIVDDLSSIFGASAS HHHHHHHHHHCCCCC	29.27	23776212
749	Phosphorylation	LSSIFGASASQSGGF HHHHHCCCCCCCCCC	28.91	23776212
751	Phosphorylation	SIFGASASQSGGFQD HHHCCCCCCCCCCCC	23.53	23776212
753	Phosphorylation	FGASASQSGGFQDVD HCCCCCCCCCCCCCC	38.09	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AUXI1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AUXI1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AUXI1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.