dbPTM

ASCC1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ASCC1_MOUSE
UniProt AC	Q9D8Z1
Protein Name	Activating signal cointegrator 1 complex subunit 1
Gene Name	Ascc1
Organism	Mus musculus (Mouse).
Sequence Length	356
Subcellular Localization	Nucleus .
Protein Description	Enhances NF-kappa-B, SRF and AP1 transactivation. May also play a role in the development of neuromuscular junction..
Protein Sequence	MDVLRPQIVTFDGRNYRKNPIQEKQYQHEEDEDFYPDSMEYSDEPCGAYEVAQTPHGFRATVSAPSLLYKHIVGKRGDTKKKIEVETKTSINIPKHGHEGEIVITGQHRNGVVSARTRIDVLLDTFRRRQPFTHFLSFFLNEVEVQERFLMFQEEVLRKCSKDRGVDSTIFQNPKKLHLTIGMLVLLSEQEIQQTCEILQRCKEEFINDISGGRPLEVEMAGIEYMNDDPAMVDVLYAKVHMKDGSNRLQELVDRVLERFQSLGLIVKEWTSVKLHATVMNTLLRKDPNAEGRYNLYTADGKYIFKERESFDGRNILKTFENFYFGSLRLNSIHISQRFTVDSFGNYASCGHVDFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	VTFDGRNYRKNPIQE EEECCCCCCCCCCHH	22.92	-
26	Phosphorylation	NPIQEKQYQHEEDED CCCHHHHCCCCCCCC	23.93	-
61	Phosphorylation	TPHGFRATVSAPSLL CCCCEEEEEECHHHH	15.67	28066266
63	Phosphorylation	HGFRATVSAPSLLYK CCEEEEEECHHHHHH	30.06	30352176
66	Phosphorylation	RATVSAPSLLYKHIV EEEEECHHHHHHHHH	30.62	28066266
90	Phosphorylation	IEVETKTSINIPKHG EEEEEECEEECCCCC	18.39	19854140
302	Ubiquitination	NLYTADGKYIFKERE EEEECCCCEEEEECC	35.40	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ASCC1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ASCC1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ASCC1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DDRGK_MOUSE	Ddrgk1	physical	25219498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ASCC1_MOUSE

Related Literatures of Post-Translational Modification