ARSF_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARSF_HUMAN
• UniProt AC: P54793
• Protein Name: Arylsulfatase F
• Gene Name: ARSF
• Organism: Homo sapiens (Human).
• Sequence Length: 590
• Subcellular Localization: Secreted .
• Protein Sequence: MRPRRPLVFMSLVCALLNTCQAHRVHDDKPNIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFLTGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNETTLAALLKKQGYSTGLIGKWHQGLNCDSRSDQCHHPYNYGFDYYYGMPFTLVDSCWPDPSRNTELAFESQLWLCVQLVAIAILTLTFGKLSGWVSVPWLLIFSMILFIFLLGYAWFSSHTSPLYWDCLLMRGHEITEQPMKAERAGSIMVKEAISFLERHSKETFLLFFSFLHVHTPLPTTDDFTGTSKHGLYGDNVEEMDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQDRVIDGRDLMPLLQGNVRHSEHEFLFHYCGSYLHAVRWIPKDDSGSVWKAHYVTPVFQPPASGGCYVTSLCRCFGEQVTYHNPPLLFDLSRDPSESTPLTPATEPLHDFVIKKVANALKEHQETIVPVTYQLSELNQGRTWLKPCCGVFPFCLCDKEEEVSQPRGPNEKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	N-linked_Glycosylation	GDLGCYGNDTMRTPH CCCCCCCCCCCCCHH	18.33	UniProtKB CARBOHYD
78	3-oxoalanine (Cys)	HISAASLCSPSRSAF HCCHHHHCCCCCCHH	5.35	-
78	Oxidation	HISAASLCSPSRSAF HCCHHHHCCCCCCHH	5.35	-
94	Phosphorylation	TGRYPIRSGMVSSGN CCCCCCCCCCCCCCC	31.77	22210691
117	N-linked_Glycosylation	VPAGLPLNETTLAAL CCCCCCCCHHHHHHH	42.50	UniProtKB CARBOHYD
130	Phosphorylation	ALLKKQGYSTGLIGK HHHHHCCCCCCCCCC	10.68	29083192
131	Phosphorylation	LLKKQGYSTGLIGKW HHHHCCCCCCCCCCC	23.87	29083192
132	Phosphorylation	LKKQGYSTGLIGKWH HHHCCCCCCCCCCCC	27.76	29083192
265	Phosphorylation	MKAERAGSIMVKEAI CCHHHHHHHHHHHHH	13.41	-
269	Acetylation	RAGSIMVKEAISFLE HHHHHHHHHHHHHHH	24.85	7668501
336	N-linked_Glycosylation	IDDFGLRNNTLVYFT HHHCCCCCCEEEEEE	51.37	UniProtKB CARBOHYD
402	Phosphorylation	RLIKEPTSLMDILPT CCCCCCCCHHHHHHH	32.20	19845377
417	Phosphorylation	VASVSGGSLPQDRVI HHHCCCCCCCCCCEE	40.16	19845377

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARSF_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARSF_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARSF_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EP300_HUMAN	EP300	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.