ARC3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARC3_ARATH
• UniProt AC: Q6F6B5
• Protein Name: Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3
• Gene Name: ARC3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 741
• Subcellular Localization: Plastid, chloroplast outer membrane; Peripheral membrane protein; Cytoplasmic side. Plastid, chloroplast stroma. Located at the site of chloroplast division on the outer surface in a ring-shaped structure at the early and middle stages of the process
• Protein Description: Z-ring accessory protein involved in the initiation of plastid division and division site placement (might functionally replace bacterial MinC). May control the rate of chloroplast expansion. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency..
• Protein Sequence: MPISMELPVFSTLRVPLFSRLALLPTFGVPFSSLGATTRLNCTSRKARRICVMCLVRDSAPIETCERAGEDGSDEFIEVLVIGSRKESIMDSCLDSPFPSLPLRFWSISKDSSGGLVLQQRLNHQDNALKTMNPIELLQSRPRAFILVASAGYGSDQVEAINILSAVRSGGNLAVAVLLKPFSFEGRKRLEEVNELARKLQQHTNFCIDIDIEVLLQKDLVTLDEALRNANNAVSMAINAASALISGMHGNFIDVMHKDLKELEGSEVKTILESYKEAKVGFGVGHNLKTSILRAIYDCPFFRPGLKDLNAIICIVASSVPLQKKDVKTILRTFRQTMEYTGDIIVSTVHEPDLEPKVRVTTFFILSSSEVETSNKGNIFSGLVPFVLNIFTRYRSQLQKETNIGLGETPVSIKDSADSTDVKTSNQNIEEFEIDSEDLLEVSENGDDSEYPLKEGEPSRNSRLDLKDENVEDFGAIQREPIANWSMDQGYQIEQKWQADSGDTAVLSLGIVNLPVGVRPSKKLNSNLSVASQLSRKADSREESFFNPNGSTKDSSDTASTLLSEKYADFTKQRNLSARASSMLEAERDSSKRWSPILEMQYRGGLFKGRCQGGLPEGKGRLVLGDGSIYDGMWHNGKRSGLGTFYFKNGDVFQGTWREDLIHGKGWFYFHKGDRWFANFWKGKASGEGRFYSKSGEIFFGHFKDGWRHGQFLCIDLDGTRYSETWDDGVLIDRKQVDAGD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
367	Phosphorylation	VTTFFILSSSEVETS EEEEEEEECCCCCCC	27.31	24243849
368	Phosphorylation	TTFFILSSSEVETSN EEEEEEECCCCCCCC	27.37	24243849
369	Phosphorylation	TFFILSSSEVETSNK EEEEEECCCCCCCCC	42.14	24243849

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARC3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARC3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARC3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FTZ21_ARATH	FTSZ2-1	physical	23715471
CDP1_ARATH	PARC6	physical	19564892
ARC3_ARATH	ARC3	physical	19564892

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.