APBP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APBP2_MOUSE
• UniProt AC: Q9DAX9
• Protein Name: Amyloid protein-binding protein 2
• Gene Name: Appbp2
• Organism: Mus musculus (Mouse).
• Sequence Length: 585
• Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton. Membrane ; Peripheral membrane protein . Associated with membranes and microtubules..
• Protein Description: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (By similarity)..
• Protein Sequence: MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFAKSHYDEAYKWCVEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSSSPQSTEEVVQSFLMAQNVEGPSC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Ubiquitination	CELEVFAKVLRALDK HHHHHHHHHHHHHCH	30.27	-
118	Acetylation	SDAAVKEKAIQVGFV CCHHHHHHHHHHHCH	45.10	19861247
141	Acetylation	GWYSDAEKVFLSCLQ CCCCCHHHHHHHHHH	39.75	19861257
412	Phosphorylation	EAHDLHLSSLQLAKK HHHHHHHHHHHHHHH	20.46	25338131
413	Phosphorylation	AHDLHLSSLQLAKKA HHHHHHHHHHHHHHH	26.88	25338131
522	Ubiquitination	YDYRGLIKLYNSIGN CCHHHHHHHHHHCCC	50.38	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APBP2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APBP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APBP2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CROCC_MOUSE	Crocc	physical	16018997

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.