ANR23_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANR23_HUMAN
• UniProt AC: Q86SG2
• Protein Name: Ankyrin repeat domain-containing protein 23
• Gene Name: ANKRD23
• Organism: Homo sapiens (Human).
• Sequence Length: 305
• Subcellular Localization: Nucleus. Sarcomeric I-band and some intercalated disks..
• Protein Description: May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression..
• Protein Sequence: MDFISIQQLVSGERVEGKVLGFGHGVPDPGAWPSDWRRGPQEAVAREKLKLEEEKKKKLERFNSTRFNLDNLADLENLVQRRKKRLRHRVPPRKPEPLVKPQSQAQVEPVGLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARDWQRGIREALQAHVAHPRTRC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	ISIQQLVSGERVEGK CCCEEHHCCCCEECE	43.45	28634298
169	Phosphorylation	KLLVAGATVDARDLL HHHHCCCEECHHHHH	20.28	28152594

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANR23_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANR23_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANR23_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYPN_HUMAN	MYPN	physical	14583192
TITIN_HUMAN	TTN	physical	14583192

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.