AN36B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AN36B_HUMAN
• UniProt AC: Q8N2N9
• Protein Name: Ankyrin repeat domain-containing protein 36B
• Gene Name: ANKRD36B
• Organism: Homo sapiens (Human).
• Sequence Length: 1353
• Protein Sequence: MERLCSDGFAFPHYYIKPYHLKRIHRAVLRGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGADPNITDVFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRDVYGKLAEDYASEAENRVIFDLIYEYKRKRYEDLPINSNPVSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Ubiquitination	LTYYDANKRDRKERT HHHHHCCCCCHHHHH	58.35	-
74	Phosphorylation	EMVHLLVSRRCELNL HHHHHHHHCCCCCCC	17.61	24719451
88	Phosphorylation	LCDREDRTPLIKAVQ CCCCCCCCHHHHHHH	34.47	24719451
183	Phosphorylation	ANVNAIDYLGRSALI CCCCHHHHHCHHHHH	12.63	-
245	Phosphorylation	YEYKRKRYEDLPINS HHHHHHHHHCCCCCC	19.48	26074081
252	Phosphorylation	YEDLPINSNPVSPQK HHCCCCCCCCCCHHH	43.14	26074081
256	Phosphorylation	PINSNPVSPQKQRAE CCCCCCCCHHHHHHH	23.91	26074081
320	Phosphorylation	EIKEGQQSGTVSPQK HHHCCCCCCCCCCCH	28.66	29396449
322	Phosphorylation	KEGQQSGTVSPQKQS HCCCCCCCCCCCHHH	24.06	29396449
324	Phosphorylation	GQQSGTVSPQKQSAQ CCCCCCCCCCHHHHH	22.81	-
340	Phosphorylation	VIFKKKVSLLNIATR HHHHHHHHHHHHHHH	35.70	19413330
346	Phosphorylation	VSLLNIATRIMGGGK HHHHHHHHHHCCCCC	19.55	21964256
354	Phosphorylation	RIMGGGKSGTVSSQK HHCCCCCCCCCCCCC	42.86	19413330
359	Phosphorylation	GKSGTVSSQKQPASK CCCCCCCCCCCCCCC	36.74	-
365	Phosphorylation	SSQKQPASKTASDKT CCCCCCCCCCCCCCC	36.90	29449344
367	Phosphorylation	QKQPASKTASDKTDS CCCCCCCCCCCCCCH	28.97	29449344
369	Phosphorylation	QPASKTASDKTDSAL CCCCCCCCCCCCHHH	44.89	29449344
390	Phosphorylation	KDGLQCGTVSSQKQQ CCCCCCCCCCHHHHH	25.49	50565575
408	Phosphorylation	ATTDEEGSVSNIATE CCCCCCCCCCCEEEE	26.17	68713883
426	Phosphorylation	GEKSGTVSSQKKPAL CCCCCCCCCCCCCCC	27.21	68713887
476	Phosphorylation	ATSVKEDSVLNIARE CCCCCCCHHHHHHHH	29.60	46164259
534	Phosphorylation	VSSHKQPSLKATSDK CCCCCCCCCCCCCCC	39.75	46164263
544	Phosphorylation	ATSDKEDSVPNMATE CCCCCCCCCCCCCCC	40.33	46164267
558	Phosphorylation	ETKDEQISGTVSCQK CCCCCCCCCCCCCCC	28.27	6589889
560	Phosphorylation	KDEQISGTVSCQKQP CCCCCCCCCCCCCCC	11.49	29083192
562	Phosphorylation	EQISGTVSCQKQPAL CCCCCCCCCCCCCCC	15.63	29083192
572	Phosphorylation	KQPALKATSDKKDSV CCCCCCCCCCCCCCC	35.55	6589893
573	Phosphorylation	QPALKATSDKKDSVS CCCCCCCCCCCCCCC	52.90	6589885
584	Phosphorylation	DSVSNIPTEIKDGQQ CCCCCCCCEEECCCC	46.69	23025827
592	Phosphorylation	EIKDGQQSGTVSSQK EEECCCCCCCCCCCC	28.66	23879269
596	Phosphorylation	GQQSGTVSSQKQPAW CCCCCCCCCCCCCCC	27.21	23879269
607	Phosphorylation	QPAWKATSVKKDSVS CCCCCCCCCCCCHHH	36.48	18452278
618	Phosphorylation	DSVSNIATEIKDGQI CHHHCCEEEECCCEE	34.15	18452278
660	Phosphorylation	EIKDGEKSGTVSPQK HHHCCCCCCCCCCCH	35.08	29396449
662	Phosphorylation	KDGEKSGTVSPQKQS HCCCCCCCCCCCHHH	25.54	29396449
664	Phosphorylation	GEKSGTVSPQKQSAQ CCCCCCCCCCHHHHH	22.81	-
680	Phosphorylation	VIFKKKVSLLNIATR HHHHHHHHHHHHHHC	35.70	-
686	Phosphorylation	VSLLNIATRITGGGK HHHHHHHHCCCCCCC	20.86	21964256
689	Phosphorylation	LNIATRITGGGKSGT HHHHHCCCCCCCCCC	26.87	30576142
696	Phosphorylation	TGGGKSGTEYPENLR CCCCCCCCCCCCCHH	39.16	30576142
718	Phosphorylation	NKDSVLNTATKMKEV CCHHHHHHHHHHHCC	31.38	29759185
720	Phosphorylation	DSVLNTATKMKEVQT HHHHHHHHHHHCCCC	29.63	29759185
868	Acetylation	HEILELEKELCSLRF HHHHHHHHHHHHHHH	69.48	18529165
921	O-linked_Glycosylation	PIKPALKSAEVELKT CCCHHHHCCEEEEEC	30.43	30379171
963	Ubiquitination	IARLRLEKDTIKNQN HHHHHHCHHHHHCCC	65.84	29967540
1141	Phosphorylation	MKDIEKMYKSGYNTM HHHHHHHHHHCHHHH	17.05	11021523
1147	Phosphorylation	MYKSGYNTMEKCIEK HHHHCHHHHHHHHHH	20.44	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AN36B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AN36B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AN36B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.