ALY2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ALY2_ARATH
• UniProt AC: Q6A333
• Protein Name: Protein ALWAYS EARLY 2
• Gene Name: ALY2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1051
• Subcellular Localization: Nucleus.
• Protein Sequence: MAPVRKSRSVNKRFTNETSPRKDAGKSKKNKLRKKLSDKLGPQWTRLELERFYDAYRKHGQEWRRVAAAIRNSRSVDMVEALFNMNRAYLSLPEGTASVAGLIAMMTDHYSVMEGSGSEGEGHDASEVPRKQQKRKRAKPQRSDSPEEVDIQQSIGSPDGCLTFLKQARANGTQRHATGKRTPRVPVQTSFMRDDREGSTPPNKRARKQFDANDDVAHFLALALTDASRRGGSPKVSESPNRRTELSDSSPIKSWGKMSRTRKSQSKHCGSSIFEEWMESSRERKLDSDKDTTLLMDMERAGEMEAPRKGKRVYKKRVKVEEAECNDSDDNGEACSATQGLRSKSQRRKAAIEASREKYSPRSPKKRDDKHTSGAFDALQALAELSASMLPANLMESELSAQLKEERTEYDMDEKSSTPEATSTSSHGEKANVEPDDSLLHAISSVENANKRKSKPSRLVSTDCDDVPTGKLQPQTSGSLRKRKPKVLGDEAPAEFSQNKSINKKELPQDENNMKSLVKTKRAGQVPAQSKQMKTVKALEESAITSDKKRPGMDIVASPKQVSDSGPTSLSQKPPNRRKKSLQKSLQEKAKSSETTHKAARSSRSLSEQELLLKDKLATSLSFPFARRRCIFEWFYSAIDHPWFSKMEFVDYLNHVGLGHIPRLTRLEWSVIKSSLGRPRRFSERFLHEEREKLKQYRESVRKHYTELRTGAREGLPTDLARPLAVGNRVIAIHPKTREIHDGKILTVDHNKCNVLFDDLGVELVMDIDCMPLNPLEYMPEGLRRQIDKCLSMKKEAQLSGNTNLGVSVLFPPCGLENVSFSMNPPLNQGDMIAPILHGKVSSNTSSPRQTNHSYITTYNKAKEAEIQRAQALQHALDEKEMEPEMLEIVKGSKTRAQAMVDAAIKAASSVKEGEDVNTMIQEALELVGKNQLLRSSMVKHHEHVNGSIEHHHNPSPSNGSEPVANNDLNSQDGSEKNAQMPSELITSCVATWLMIQMCTERQYPPADVAQLIDAAVTSLQPRCPQNLPIYREIQTCMGRIKTQIMSLVPT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
199	Phosphorylation	MRDDREGSTPPNKRA CCCCCCCCCCCCHHH	32.75	25561503
200	Phosphorylation	RDDREGSTPPNKRAR CCCCCCCCCCCHHHH	54.33	25561503
237	Phosphorylation	RGGSPKVSESPNRRT CCCCCCCCCCCCCCC	38.18	25561503
239	Phosphorylation	GSPKVSESPNRRTEL CCCCCCCCCCCCCCC	21.70	25561503
247	Phosphorylation	PNRRTELSDSSPIKS CCCCCCCCCCCCCCC	29.25	25561503
249	Phosphorylation	RRTELSDSSPIKSWG CCCCCCCCCCCCCCC	34.34	25561503
250	Phosphorylation	RTELSDSSPIKSWGK CCCCCCCCCCCCCCC	35.32	25561503
328	Phosphorylation	EEAECNDSDDNGEAC EEECCCCCCCCCCCC	32.64	19880383
355	Phosphorylation	RKAAIEASREKYSPR HHHHHHHHHHHCCCC	28.34	19880383
558	Phosphorylation	PGMDIVASPKQVSDS CCCCEEECCCCCCCC	23.03	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ALY2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ALY2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ALY2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNL1_ARATH	SNL1	physical	19962994

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.