dbPTM

ALP11_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ALP11_SCHPO
UniProt AC	Q10235
Protein Name	Cell polarity protein alp11
Gene Name	alp11
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	234
Subcellular Localization	Cytoplasm, cytoskeleton .
Protein Description	Required for microtubule function and cell polarity. Involved in the proper folding of alpha-tubulin..
Protein Sequence	MNEITLFIKSSSANAERRINPQWTVSQLKTKLVPIVGTPEQYQKLTYEPASSTVPGHVFTSEEENLDLGEFKLQPLGTIVVEDTRPPHLRLDFDDLSQVDKYVMPREQYENRTDSVYAWKKRNQLGRFNPDFEASKASRQESLKRELVDLQKNLNSRCCAAGERYGTIRYIGLVPEINNDNLWVGVEFDEPVGKNDGTVSGKRYFNAKNKHGSFLRSSEVEVGDFPPEDILEGL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
213	Phosphorylation	NAKNKHGSFLRSSEV CCCCCCCCCCCCCEE	22.34	28889911
218	Phosphorylation	HGSFLRSSEVEVGDF CCCCCCCCEEECCCC	38.95	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ALP11_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ALP11_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ALP11_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ALP21_SCHPO	alp21	genetic	10473641
ALP21_SCHPO	alp21	genetic	10683446
ALP1_SCHPO	alp1	genetic	10473641
ALP1_SCHPO	alp1	genetic	10683446
ALP21_SCHPO	alp21	physical	10473641
TBA2_SCHPO	atb2	physical	10473641
TBA2_SCHPO	atb2	genetic	10473641

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ALP11_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-213, AND MASSSPECTROMETRY.	18257517 [Abstract]