ADK1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ADK1_ARATH
• UniProt AC: Q9SF85
• Protein Name: Adenosine kinase 1
• Gene Name: ADK1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 344
• Protein Description: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Essential to sustain methyl recycling..
• Protein Sequence: MASSDFDGILLGMGNPLLDVSAVVDQQFLDKYDIKLNNAILAEDKHLPMYDEMSQKFNVEYIAGGATQNSIKVAQWMLQVPGATSYMGSIGKDKYGEAMKKDATAAGVYVHYYEDEATPTGTCGVCVLGGERSLIANLSAANCYKVEHLKKPENWALVEKAKFYYIAGFFLTVSPESIQLVREHAAANNKVFTMNLSAPFICEFFKDVQEKCLPYMDYIFGNETEARTFSRVHGWETDDVEQIAIKMSQLPKASGTYKRTTVITQGADPVVVAEDGKVKKYPVIPLPKEKLVDTNGAGDAFVGGFLSQLVHGKGIEECVRAGCYASNVVIQRSGCTYPEKPDFN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
49	Sulfoxidation	AEDKHLPMYDEMSQK HCCCCCCCCHHHHHH	9.18	25693801
53	Sulfoxidation	HLPMYDEMSQKFNVE CCCCCHHHHHHCCEE	4.74	25693801
89	Phosphorylation	GATSYMGSIGKDKYG CCCCCCCCCCCCCCH	16.19	22074104
99	Sulfoxidation	KDKYGEAMKKDATAA CCCCHHHHHHCCCEE	4.89	25693801
323	S-nitrosylation	EECVRAGCYASNVVI HHHHHCCCCCCCEEE	2.21	22115780

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ADK1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ADK1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ADK1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SAHH1_ARATH	MEE58	physical	21976714

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.