ACPM_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ACPM_DROME
• UniProt AC: Q94519
• Protein Name: Acyl carrier protein, mitochondrial
• Gene Name: ND-ACP {ECO:0000312|FlyBase:FBgn0011361}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 152
• Subcellular Localization: Mitochondrion.
• Protein Description: Carrier of the growing fatty acid chain in fatty acid biosynthesis. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity)..
• Protein Sequence: MSFTQIARSCSRLAATLAPRRVASGILIQSQASRMMHRIAVPSMTSQLSQECRGRWQTQLVRKYSAKPPLSLKLINERVLLVLKLYDKIDPSKLNVESHFINDLGLDSLDHVEVIMAMEDEFGFEIPDSDAEKLLKPADIIKYVADKEDVYE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	ILIQSQASRMMHRIA CCHHHHHHHHHHHHH	17.05	22668510
43	Phosphorylation	MHRIAVPSMTSQLSQ HHHHHHCHHHHHHCH	28.26	22668510
45	Phosphorylation	RIAVPSMTSQLSQEC HHHHCHHHHHHCHHH	20.05	22668510
67 (in isoform 2)	Acetylation	-	41.02	-
72 (in isoform 2)	Acetylation	-	7.43	-
79 (in isoform 2)	Acetylation	-	3.85	-
88	Acetylation	LVLKLYDKIDPSKLN HHHHHHHCCCHHHCC	35.14	21791702
108	O-(pantetheine 4'-phosphoryl)serine	INDLGLDSLDHVEVI CCCCCCCCCCCEEEH	40.51	-
108	Phosphorylation	INDLGLDSLDHVEVI CCCCCCCCCCCEEEH	40.51	-
136	Acetylation	SDAEKLLKPADIIKY CHHHHHCCHHHHHHH	48.90	21791702
142	Acetylation	LKPADIIKYVADKED CCHHHHHHHHCCHHH	33.72	21791702
147	Acetylation	IIKYVADKEDVYE-- HHHHHCCHHHHCC--	46.18	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ACPM_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ACPM_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ACPM_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BCN92_DROME	bcn92	physical	22036573
LIPT2_DROME	CG9804	physical	22036573
MMD4_DROME	mod(mdg4)	physical	27025476

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.