dbPTM

ABHEA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ABHEA_HUMAN
UniProt AC	Q9BUJ0
Protein Name	Protein ABHD14A {ECO:0000305}
Gene Name	ABHD14A {ECO:0000312\|HGNC:HGNC:24538}
Organism	Homo sapiens (Human).
Sequence Length	271
Subcellular Localization	Cytoplasm. Membrane Single-pass type II membrane protein .
Protein Description	Possible role in granule neuron development..
Protein Sequence	MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
67	N-linked_Glycosylation	SCLWGDPNVTVLAGL CCCCCCCCEEEEEEC	47.00	UniProtKB CARBOHYD
120	Phosphorylation	LGTLQLLSQRGYRAV HHHHHHHHHCCCCEE	26.82	24719451
141	Ubiquitination	FGNSAPSKEASTEAG CCCCCCCHHHCCHHH	57.13	-
145	Phosphorylation	APSKEASTEAGRAAL CCCHHHCCHHHHHHH	36.58	46157057
201	N-linked_Glycosylation	IAPTSTQNYTQEQFW ECCCCCCCCCHHHEE	41.74	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ABHEA_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ABHEA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ABHEA_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PSF3_HUMAN	GINS3	physical	22863883
PA1B2_HUMAN	PAFAH1B2	physical	22863883
GDS1_HUMAN	RAP1GDS1	physical	22863883

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ABHEA_HUMAN

Related Literatures of Post-Translational Modification