AB1C_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AB1C_ARATH
• UniProt AC: Q9C8G9
• Protein Name: ABC transporter C family member 1
• Gene Name: ABCC1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1622
• Subcellular Localization: Vacuole membrane ; Multi-pass membrane protein . Tonoplast.
• Protein Description: Pump for glutathione S-conjugates. Mediates the transport of S-(2,4-dinitrophenyl)-glutathione (DNP-GS), GSSG, cyanidin 3-glucoside-GS (C3G-GS) and metolachlor-GS (MOC-GS)..
• Protein Sequence: MGFEPLDWYCKPVPNGVWTKTVDYAFGAYTPCAIDSFVLGISHLVLLILCLYRLWLITKDHKVDKFCLRSKWFSYFLALLAAYATAEPLFRLVMRISVLDLDGAGFPPYEAFMLVLEAFAWGSALVMTVVETKTYIHELRWYVRFAVIYALVGDMVLLNLVLSVKEYYGSFKLYLYISEVAVQVAFGTLLFVYFPNLDPYPGYTPVGTENSEDYEYEELPGGENICPERHANLFDSIFFSWLNPLMTLGSKRPLTEKDVWHLDTWDKTETLMRSFQKSWDKELEKPKPWLLRALNNSLGGRFWWGGFWKIGNDCSQFVGPLLLNELLKSMQLNEPAWIGYIYAISIFVGVVLGVLCEAQYFQNVMRVGYRLRSALIAAVFRKSLRLTNEGRKKFQTGKITNLMTTDAESLQQICQSLHTMWSAPFRIIVALVLLYQQLGVASIIGALFLVLMFPIQTVIISKTQKLTKEGLQRTDKRIGLMNEVLAAMDTVKCYAWENSFQSKVQTVRDDELSWFRKAQLLSAFNMFILNSIPVLVTVVSFGVFSLLGGDLTPARAFTSLSLFSVLRFPLFMLPNIITQMVNANVSLNRLEEVLSTEERVLLPNPPIEPGQPAISIRNGYFSWDSKADRPTLSNINLDIPLGSLVAVVGSTGEGKTSLISAMLGELPARSDATVTLRGSVAYVPQVSWIFNATVRDNILFGAPFDQEKYERVIDVTALQHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVCILDDPLSALDAHVGQQVFEKCIKRELGQTTRVLVTNQLHFLSQVDKILLVHEGTVKEEGTYEELCHSGPLFQRLMENAGKVEDYSEENGEAEVDQTSVKPVENGNANNLQKDGIETKNSKEGNSVLVKREERETGVVSWKVLERYQNALGGAWVVMMLVICYVLTQVFRVSSSTWLSEWTDSGTPKTHGPLFYNIVYALLSFGQVSVTLINSYWLIMSSLYAAKKMHDAMLGSILRAPMVFFQTNPLGRIINRFAKDMGDIDRTVAVFVNMFMGSIAQLLSTVILIGIVSTLSLWAIMPLLVVFYGAYLYYQNTSREIKRMDSTTRSPVYAQFGEALNGLSSIRAYKAYDRMAEINGRSMDNNIRFTLVNMAANRWLGIRLEVLGGLMVWLTASLAVMQNGKAANQQAYASTMGLLLSYALSITSSLTAVLRLASLAENSLNSVERVGNYIEIPSEAPLVIENNRPPPGWPSSGSIKFEDVVLRYRPELPPVLHGVSFLISPMDKVGIVGRTGAGKSSLLNALFRIVELEKGRILIDECDIGRFGLMDLRKVLGIIPQAPVLFSGTVRFNLDPFSEHNDADLWESLERAHLKDTIRRNPLGLDAEVTEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDVLIQKTIREEFKSCTMLIIAHRLNTIIDCDKVLVLDSGKVQEFSSPENLLSNGESSFSKMVQSTGTANAEYLRSITLENKRTREANGDDSQPLEGQRKWQASSRWAAAAQFALAVSLTSSHNDLQSLEIEDDNSILKKTKDAVVTLRSVLEGKHDKEIEDSLNQSDISRERWWPSLYKMVEGLAVMSRLARNRMQHPDYNLEGKSFDWDNVEM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
490	Phosphorylation	EVLAAMDTVKCYAWE HHHHHHHHCHHHHHC	14.58	19880383
631	Phosphorylation	DSKADRPTLSNINLD CCCCCCCCCCCCEEC	43.65	25368622
633	Phosphorylation	KADRPTLSNINLDIP CCCCCCCCCCEECCC	37.84	25368622
643	Phosphorylation	NLDIPLGSLVAVVGS EECCCCCCEEEEEEC	27.61	25368622
650	Phosphorylation	SLVAVVGSTGEGKTS CEEEEEECCCCCHHH	22.94	25368622
651	Phosphorylation	LVAVVGSTGEGKTSL EEEEEECCCCCHHHH	33.07	25368622
731	Phosphorylation	LLPGGDLTEIGERGV ECCCCCCCEEHHCCE	30.23	28295753
1483	Phosphorylation	ANAEYLRSITLENKR CCHHHHHHHEECCCC	19.82	25561503
1485	Phosphorylation	AEYLRSITLENKRTR HHHHHHHEECCCCHH	29.30	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AB1C_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AB1C_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AB1C_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FKB42_ARATH	TWD1	physical	15133126

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.