| UniProt ID | AATC2_HUMAN | |
|---|---|---|
| UniProt AC | Q8NHS2 | |
| Protein Name | Putative aspartate aminotransferase, cytoplasmic 2 | |
| Gene Name | GOT1L1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 421 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | ||
| Protein Sequence | MPTLSVFMDVPLAHKLEGSLLKTYKQDDYPNKIFLAYRVCMTNEGHPWVSLVVQKTRLQISQDPSLNYEYLPTMGLKSFIQASLALLFGKHSQAIVENRVGGVHTVGDSGAFQLGVQFLRAWHKDARIVYIISSQKELHGLVFQDMGFTVYEYSVWDPKKLCMDPDILLNVVEQIPHGCVLVMGNIIDCKLTPSGWAKLMSMIKSKQIFPFFDIPCQGLYTSDLEEDTRILQYFVSQGFEFFCSQSLSKNFGIYDEGVGMLVVVAVNNQQLLCVLSQLEGLAQALWLNPPNTGARVITSILCNPALLGEWKQSLKEVVENIMLTKEKVKEKLQLLGTPGSWGHITEQSGTHGYLGLNSQQVEYLVRKKHIYIPKNGQINFSCINANNINYITEGINEAVLLTESSEMCLPKEKKTLIGIKL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 19 | Phosphorylation | LAHKLEGSLLKTYKQ CHHHCCCCHHHHCCC | 22.58 | 24719451 | |
| 42 | Phosphorylation | LAYRVCMTNEGHPWV EEEEEHHCCCCCCEE | 25.62 | 25022875 | |
| 194 | Phosphorylation | IDCKLTPSGWAKLMS EECEECHHHHHHHHH | 41.55 | 23532336 | |
| 201 | Phosphorylation | SGWAKLMSMIKSKQI HHHHHHHHHHHHCCC | 28.00 | 27135362 | |
| 249 | N6-(pyridoxal phosphate)lysine | FCSQSLSKNFGIYDE EECCHHHHCCCCCCC | 62.68 | - | |
| 249 | Other | FCSQSLSKNFGIYDE EECCHHHHCCCCCCC | 62.68 | - | |
| 324 | Phosphorylation | VVENIMLTKEKVKEK HHHHHCCCHHHHHHH | 21.56 | 29743597 | |
| 325 | Ubiquitination | VENIMLTKEKVKEKL HHHHCCCHHHHHHHH | 52.13 | - | |
| 414 | Malonylation | MCLPKEKKTLIGIKL CCCCCCCCEEEEEEC | 50.05 | 26320211 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AATC2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AATC2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AATC2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A1AT_HUMAN | SERPINA1 | physical | 28514442 | |
| APOA1_HUMAN | APOA1 | physical | 28514442 | |
| AATC_HUMAN | GOT1 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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