ZSWM9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSWM9_HUMAN
• UniProt AC: Q86XI8
• Protein Name: Uncharacterized protein ZSWIM9
• Gene Name: ZSWIM9 {ECO:0000312|HGNC:HGNC:34495}
• Organism: Homo sapiens (Human).
• Sequence Length: 627
• Protein Sequence: MERPEPPPGTAAGQEEQELRERAFFSWAEFSRFFDAWCQQRLALFFVKSSMHLARCRWASAPPLYTLIDVLKYSYVRLVCKDVRAPSRPAVGPPQPGCPAFIIVKLSPLRDRLVVTECQLTHSHPACPLEFAYYFRPGHLLANACLPVRTTNKISKQFVAPADVRRLLSYCKGRDHGVLDALHVLEGLFRTDPEAKVKLVFVEDQAVVETVFFLTSRTRALLRRFPRMLLVDRLPGLQGALDLLAVLCVDGSGRARQAACCVARPGTPSLLRFALASLLQSAPDVKGRVRCLTAGPEVAAQLPAVRQLLPCARVQICRAQGLETLFSKAQELGGAGREDPGLWSRLCRLAGASSPAAYDEALAELHAHGPAAFVDYFERNWEPRRDMWVRFRAFEAARDLDACALVRGHRRRLLRRLSPSRGVAQCLRDLVAMQWADAAGEAVPEGPDGGGPWLEDEPGRGAQGENERVRGLETGDWGGAPKEGSIWRGAQMEKEWARALETRDWGGAQFEGEKGRALQIRDWRGGRLENQKPRGLEGGVLRGSKLEKGHLRGPEIRDWRGPQLEGEKDWGLEGYVWRGSQLEDQALRGLEGYTWRVAQLEDRRSTTDLRGTQFDYERGKGESTEDR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	ALFFVKSSMHLARCR HHHHHHHCHHHHHCH		19845377
87	Phosphorylation	CKDVRAPSRPAVGPP ECCCCCCCCCCCCCC		23532336
96	Ubiquitination	PAVGPPQPGCPAFII CCCCCCCCCCCEEEE		22505724
107	Phosphorylation	AFIIVKLSPLRDRLV EEEEEECCCCCCCEE		30278072
138	Ubiquitination	FAYYFRPGHLLANAC EEEEECCCCHHHCEE		23503661
156	Ubiquitination	RTTNKISKQFVAPAD ECCCCCCCCCCCHHH		29967540
172	Ubiquitination	RRLLSYCKGRDHGVL HHHHHHHCCCCCCHH		-
214	Ubiquitination	VVETVFFLTSRTRAL HEEHHHHHHHHHHHH		22505724
256	Ubiquitination	VDGSGRARQAACCVA CCCCCHHHHHHHEEE		23503661
267	Phosphorylation	CCVARPGTPSLLRFA HEEECCCCHHHHHHH		20068231
269	Phosphorylation	VARPGTPSLLRFALA EECCCCHHHHHHHHH		20068231
277	Phosphorylation	LLRFALASLLQSAPD HHHHHHHHHHHHCCC		20068231
281	Phosphorylation	ALASLLQSAPDVKGR HHHHHHHHCCCCCCC		20068231
286	Ubiquitination	LQSAPDVKGRVRCLT HHHCCCCCCCEEEEC		21906983
299	Ubiquitination	LTAGPEVAAQLPAVR ECCCHHHHHCCHHHH		22505724
313	Ubiquitination	RQLLPCARVQICRAQ HHHHCCCCHHHHHHC		22505724
327	Phosphorylation	QGLETLFSKAQELGG CCHHHHHHHHHHHCC		24719451
328	Ubiquitination	GLETLFSKAQELGGA CHHHHHHHHHHHCCC		21906983
341	Ubiquitination	GAGREDPGLWSRLCR CCCCCCCCHHHHHHH		23503661
355	Ubiquitination	RLAGASSPAAYDEAL HHHCCCCHHHHHHHH		23503661
482	Ubiquitination	GDWGGAPKEGSIWRG CCCCCCCCCCCCCCH		-
485	Phosphorylation	GGAPKEGSIWRGAQM CCCCCCCCCCCHHHH		24719451
494	Ubiquitination	WRGAQMEKEWARALE CCHHHHHHHHHHHHH		29967540
514	Ubiquitination	GAQFEGEKGRALQIR CCCCCCCCCCEEEEE		29967540
568	Ubiquitination	GPQLEGEKDWGLEGY CCCCCCCCCCCCCCE		-
605	Phosphorylation	AQLEDRRSTTDLRGT EEECCCCCCCCCCCC		28555341
726 (in isoform 2)	Phosphorylation	-		28111955
738 (in isoform 2)	Phosphorylation	-		28111955
743 (in isoform 2)	Phosphorylation	-		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSWM9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSWM9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSWM9_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZSWM9_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.