ZSWM6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSWM6_HUMAN
• UniProt AC: Q9HCJ5
• Protein Name: Zinc finger SWIM domain-containing protein 6
• Gene Name: ZSWIM6
• Organism: Homo sapiens (Human).
• Sequence Length: 1215
• Protein Sequence: MAERGQQPPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGGDETRLPFRRGIALLESGCVDNVLQVGFHLSGTVTEPAIQSEPETVCNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITEQFMADPRLSLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKASWLKQLKKWNSVDVCPWEDGNHGSELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLQHIISSDLYTNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAIAIVNTLRRQQQKQLEMFRTQKKELPHKNITSITNLEGWVGHPLDPVGTLFSSLMEACRIDDENLSGFSDFTENMGQCKSLEYQHLPAHKFLEEGESYLTLAVEVALIGLGQQRIMPDGLYTQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEIIHRESVPMHTFAKYLFTSLLPHDAELAYKIALRAMRLLVLESTAPSGDLTRPHHIASVVPNRYPRWFTLSHIESQQCELASTMLTAAKGDVRRLETVLESIQKNIHSSSHIFKLAQDAFKIATLMDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATEVGVYALDSIMQTWFTLFTPTEATSIVATTVMSNSTIVRLHLDCHQQEKLASSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYTQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLHGRRNSGKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYSEFIEFLSKARETFLMAHDGHIQFTQFIDNLKQIYKGKKKLMMLVRERFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Ubiquitination	GQQPPPAKRLCCRPG CCCCCCCCCCCCCCC	52.24	27667366
73	Phosphorylation	LPPGKTQSPESLLDI CCCCCCCCHHHHHHH	35.55	28555341
76	Phosphorylation	GKTQSPESLLDIAAR CCCCCHHHHHHHHHH	37.30	-
424	Phosphorylation	FMADPRLSLWRQQGT HHCCCCHHHHHHHCC	27.45	24719451
602	Sumoylation	TLRRQQQKQLEMFRT HHHHHHHHHHHHHHH	53.14	-
602	Sumoylation	TLRRQQQKQLEMFRT HHHHHHHHHHHHHHH	53.14	-
609	Phosphorylation	KQLEMFRTQKKELPH HHHHHHHHCCCCCCC	33.21	-
669	Phosphorylation	ENMGQCKSLEYQHLP CCCCCCCCCEEECCC	33.78	28555341
724	Phosphorylation	RNEEQLISKLQEIEL CCHHHHHHHHHHCCC	35.59	24719451
725	Ubiquitination	NEEQLISKLQEIELD CHHHHHHHHHHCCCC	47.39	29967540
752	Phosphorylation	FLLEAGPYSGLGEII HHHHCCCCCCHHHHH	17.91	-
753	Phosphorylation	LLEAGPYSGLGEIIH HHHCCCCCCHHHHHC	30.58	-
772	Phosphorylation	PMHTFAKYLFTSLLP CHHHHHHHHHHHCCC	12.01	-
786	Phosphorylation	PHDAELAYKIALRAM CCCHHHHHHHHHHHH	18.62	-
839	Phosphorylation	SQQCELASTMLTAAK HHHHHHHHHHHHHCH	27.29	24043423
840	Phosphorylation	QQCELASTMLTAAKG HHHHHHHHHHHHCHH	15.59	24043423
843	Phosphorylation	ELASTMLTAAKGDVR HHHHHHHHHCHHHHH	17.47	24043423
861	Ubiquitination	TVLESIQKNIHSSSH HHHHHHHHHCCCCHH	57.08	-
885	Phosphorylation	KIATLMDSLPDITLL HHHHHHHHCCCCEEH	28.03	-
908	Phosphorylation	QVMRMTLSTLNWRRR HHHHHHHHHCCHHHH	22.98	29523821
909	Phosphorylation	VMRMTLSTLNWRRRE HHHHHHHHCCHHHHH	27.50	29523821
978	Phosphorylation	HQQEKLASSARTLAL HHHHHHHHHHHHHHH	34.66	-
979	Phosphorylation	QQEKLASSARTLALQ HHHHHHHHHHHHHHH	19.03	-
1096	Ubiquitination	AIIPLVVKSVKCATV HHHHHHHHHCHHHHH	41.89	32015554
1097	Phosphorylation	IIPLVVKSVKCATVL HHHHHHHHCHHHHHH	18.39	-
1112	Phosphorylation	SDILRRCTLTTPGMV HHHHHHCCCCCCCCE	25.90	24719451
1114	Phosphorylation	ILRRCTLTTPGMVGL HHHHCCCCCCCCEEE	16.88	24043423
1115	Phosphorylation	LRRCTLTTPGMVGLH HHHCCCCCCCCEEEC	22.43	24043423
1127	Phosphorylation	GLHGRRNSGKLMSLD EECCCCCCCCCCCCC	35.18	24719451
1129	Acetylation	HGRRNSGKLMSLDKA CCCCCCCCCCCCCCH	40.62	25953088
1132	Phosphorylation	RNSGKLMSLDKAPLR CCCCCCCCCCCHHHH	43.80	24719451
1145	Phosphorylation	LRQLLDATIGAYINT HHHHHHHHHHHHHCC	21.43	-
1149	Phosphorylation	LDATIGAYINTTHSR HHHHHHHHHCCCHHC	6.89	-
1173	Phosphorylation	SEFIEFLSKARETFL HHHHHHHHHHHHHHH	29.59	21815630

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSWM6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSWM6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSWM6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZSWM6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.