ZSWM5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSWM5_HUMAN
• UniProt AC: Q9P217
• Protein Name: Zinc finger SWIM domain-containing protein 5
• Gene Name: ZSWIM5
• Organism: Homo sapiens (Human).
• Sequence Length: 1185
• Protein Sequence: MADGGEREELLSPSPVSPAKRQCSWPSPQAHHPRGSPGAAGGGAGGVGSSCLVLGARPHLQPDSLLDCAAKTVAEKWAYERVEERFERIPEPVQRRIVYWSFPRNEREICMYSSFQYRGGPGAGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGASPGLGAGAGAAGCGGEGLPFRRGIRLLDSGSVENVLQVGFHLSGTVTELATASEPAVTYKVAISFDRCKITSVTCGCGNKDIFYCAHVVALSLYRIRKPDQVKLRLPISETLFQMNRDQLQKFIQYLITAHHTEVLPTAQKLADEILSSNSEINQVNGAPDPTAGASIDDENCWHLDEEQVKEQVKLFLSQGGYCGSGKQLNSMFAKVREMLRMRDSNGARMLTLITEQFVADPRLTLWRQQGTNMTDKCRQLWDELGALWVCIILNPHCKLEEKSCWLQQLQKWSDLDVCPLEDGNYGHELPNITNALPQSAIHSPDSLSRPRRTVFTRAIEGRELHWQDSHLQRIISSDVYTAPACQRESERLLFNSQGQPLWLEHVPTACARVDALRSHGYPKEALRLTVAIINTLRLQQQRQLEIYKHQKKELLQRGTTTITNLEGWVGHPLDPIDCLFLTLTEACRLNDDGYLEMSDMNESRPPVYQHVPVAAGSPNSSESYLSLALEVALMGLGQQRLMPEGLYAQDKVCRNEEQLLSQLQELQLDDELVQTLQKQCILLLEGGPFSGLGEVIHRESVPMHTFAKYLFSALLPHDPDLSYKLALRAMRLPVLENSASAGDTSHPHHMVSVVPSRYPRWFTLGHLESQQCELASTMLTAAKGDTLRLRTILEAIQKHIHSSSLIFKLAQDAFKIATPTDSSTDSTLLNVALELGLQVMRMTLSTLNWRRREMVRWLVTCATEVGVRALVSILQSWYTLFTPTEATSIVAATAVSHTTILRLSLDYPQREELASCARTLALQCAMKDPQSCALSALTLCEKDHIAFEAAYQIAIDAAAGGMTHSQLFTIARYMELRGYPLRAFKLASLAMSHLNLAYNQDTHPAINDVLWACALSHSLGKNELAALIPLVVKSVHCATVLSDILRRCTVTAPGLAGIPGRRSSGKLMSTDKAPLRQLLDATINAYINTTHSRLTHISPRHYGEFIEFLSKARETFLLPQDGHLQFAQFIDNLKQIYKGKKKLMLLVRERFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	LLSPSPVSPAKRQCS CCCCCCCCCCCCCCC	23.64	21815630
99	Phosphorylation	PVQRRIVYWSFPRNE CCHHHHEEEECCCCC	7.92	26074081
101	Phosphorylation	QRRIVYWSFPRNERE HHHHEEEECCCCCCE	14.00	26074081
112	Phosphorylation	NEREICMYSSFQYRG CCCEEEEEEEEEECC	9.21	26074081
113	Phosphorylation	EREICMYSSFQYRGG CCEEEEEEEEEECCC	9.59	26074081
114	Phosphorylation	REICMYSSFQYRGGP CEEEEEEEEEECCCC	10.01	26074081
117	Phosphorylation	CMYSSFQYRGGPGAG EEEEEEEECCCCCCC	14.82	26074081
205	Phosphorylation	VGFHLSGTVTELATA EEEEEEEEEEEEEEC	22.37	-
207	Phosphorylation	FHLSGTVTELATASE EEEEEEEEEEEECCC	25.72	-
263	Sumoylation	IRKPDQVKLRLPISE CCCCCCEEEECCCCH	23.43	-
263	Sumoylation	IRKPDQVKLRLPISE CCCCCCEEEECCCCH	23.43	-
359	Acetylation	GGYCGSGKQLNSMFA CCCCCCHHHHHHHHH	54.00	7962811
367	Acetylation	QLNSMFAKVREMLRM HHHHHHHHHHHHHHC	30.47	7962823
809	Phosphorylation	SQQCELASTMLTAAK HHHHHHHHHHHHHCC	27.29	24043423
810	Phosphorylation	QQCELASTMLTAAKG HHHHHHHHHHHHCCC	15.59	24043423
813	Phosphorylation	ELASTMLTAAKGDTL HHHHHHHHHCCCCHH	17.47	24043423
853	Phosphorylation	AFKIATPTDSSTDST HHCCCCCCCCCCCHH	44.13	-
857	Phosphorylation	ATPTDSSTDSTLLNV CCCCCCCCCHHHHHH	37.61	-
860	Phosphorylation	TDSSTDSTLLNVALE CCCCCCHHHHHHHHH	37.77	-
878	Phosphorylation	QVMRMTLSTLNWRRR HHHHHHHHHCCHHHH	22.98	29523821
879	Phosphorylation	VMRMTLSTLNWRRRE HHHHHHHHCCHHHHH	27.50	29523821
1096	Phosphorylation	AGIPGRRSSGKLMST CCCCCCCCCCCCCCC	41.92	-
1097	Phosphorylation	GIPGRRSSGKLMSTD CCCCCCCCCCCCCCC	37.83	-
1102	Phosphorylation	RSSGKLMSTDKAPLR CCCCCCCCCCCHHHH	43.84	21060948
1103	Phosphorylation	SSGKLMSTDKAPLRQ CCCCCCCCCCHHHHH	27.79	21060948
1143	Phosphorylation	GEFIEFLSKARETFL HHHHHHHHHHHHHCC	29.59	21815630

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSWM5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSWM5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSWM5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZSWM5_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.