ZSWM4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSWM4_MOUSE
• UniProt AC: Q8C7B8
• Protein Name: Zinc finger SWIM domain-containing protein 4
• Gene Name: Zswim4
• Organism: Mus musculus (Mouse).
• Sequence Length: 1101
• Protein Sequence: MEPPAAKRSRGCPAGDEPGTGARRSRPEPLLDLSAKRVAESWAFEQVEERFSRVPEPVQKRIVFWSFPRSEREICMYSSLGYQPPEGEQDTRVPFTRGLHLLQSGAVDRVLQVGFHLSGNIREVGGPGEPEHLYHVSISFDRCKITSVSCGCDNRDLFYCAHVVALSLYRIRHARQVELRLPISETLSQMNRDQLQKFVQYLISAHHTEVLPTAQRLADEILLLGSEINLVHGAPDPTAGAGTEDANCWHLDEEQIQEQVKQLLSNGGHYGASQQLRSMFSKVREMLRARDSNGARMLILMTEQFLQDPRLALWRQQGAGMTDKCRQLWDELGALWVCVILSPHCKPDERSGWLQLLGTWDKLDVCPLEEGNYSLDIPSLQPALTSRTGSEDEEEVTAASPRRTVFSRALQAGELHWNDSHLQRILASDSCGPTLTGSMGSDKPTFDPQGHPIWLGEPFPTACARVDTLRAHGYPHKALRLACAIINTLRLQRRHQLESYKQQKKELLQKGATGVTSTEGWVGHPLDPIGCLCRALLEACRLEEEPHSLFPDSAPEKRKLAYQHVLVPGSPGESYLALALEVALLGLGQQRALPEGLYAQDKVVRNEEQLLALLEEVELDERLVQVLRKQAGLLLEGGPFSGFGEVIFRESVPMHTCARYLFTALLPHDPDLAFRLALRAMRLPVLETTFPAGESHPNPLDSIMSNRFPRWFILGHLETRQCELASTMLTAAKGDTKWLHAVLGSVQQNIHSPALLFKLAQDACKTATPASAPPDTVLLGIALELGLQVMRMTLNTMTWRRREMVRWLVSCATEIGPPALMSIMKNWYSLFTPVEAVTIVAVTGTTHATLLRLQLDTAGREELWACARTLALQCAMKDPQNCALPALTLCEKNHAAFEAAYQIVLDAAAGGLGHAHLFTVARYMEHRGLPLRAYKLATLALAQLSIAFNQDSHPAVNDVLWACSLSHSLGRHELSAIVPLIIRSIHCAPMLSDILRRWTLSAPGLGPLGARRATKPLGTDRAPLCQLLDAAVAAYITTSHSRLTHISPRHYGDFIEFLGKARETFLLAPDGHLQFAQFLENLKQTYKGKKKLMLLVRERFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	EPPAAKRSRGCPAGD CCCHHHHCCCCCCCC	32.11	29550500
428	Phosphorylation	HLQRILASDSCGPTL HHHHHHHCCCCCCCC	26.98	25293948
430	Phosphorylation	QRILASDSCGPTLTG HHHHHCCCCCCCCCC	20.62	25293948
434	Phosphorylation	ASDSCGPTLTGSMGS HCCCCCCCCCCCCCC	23.41	25293948
436	Phosphorylation	DSCGPTLTGSMGSDK CCCCCCCCCCCCCCC	29.68	-
722	S-nitrosocysteine	GHLETRQCELASTML EECCHHHHHHHHHHH	4.11	-
722	S-nitrosylation	GHLETRQCELASTML EECCHHHHHHHHHHH	4.11	21278135
752	Phosphorylation	SVQQNIHSPALLFKL HHHHCCCCHHHHHHH	14.20	17203969

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSWM4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSWM4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSWM4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ZSWM4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Protein phosphorylation and expression profiling by Yin-yangmultidimensional liquid chromatography (Yin-yang MDLC) massspectrometry.";
Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.;
J. Proteome Res. 6:250-262(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-752, AND MASSSPECTROMETRY.
PubMed: 17203969