ZSCA2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSCA2_HUMAN
• UniProt AC: Q7Z7L9
• Protein Name: Zinc finger and SCAN domain-containing protein 2
• Gene Name: ZSCAN2
• Organism: Homo sapiens (Human).
• Sequence Length: 614
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis..
• Protein Sequence: MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMILEDDSWVQEAVLQEDGPESEPFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQMLTMLPKEIQAWLQEHRPESSEEAAALVEDLTQTLQDSDFEIQSENGENCNQDMFENESRKIFSEMPEGESAQHSDGESDFERDAGIQRLQGHSPGEDHGEVVSQDREVGQLIGLQGTYLGEKPYECPQCGKTFSRKSHLITHERTHTGEKYYKCDECGKSFSDGSNFSRHQTTHTGEKPYKCRDCGKSFSRSANLITHQRIHTGEKPFQCAECGKSFSRSPNLIAHQRTHTGEKPYSCPECGKSFGNRSSLNTHQGIHTGEKPYECKECGESFSYNSNLIRHQRIHTGEKPYKCTDCGQRFSQSSALITHRRTHTGEKPYQCSECGKSFSRSSNLATHRRTHMVEKPYKCGVCGKSFSQSSSLIAHQGMHTGEKPYECLTCGESFSWSSNLLKHQRIHTGEKPYKCSECGKCFSQRSQLVVHQRTHTGEKPYKCLMCGKSFSRGSILVMHQRAHLGDKPYRCPECGKGFSWNSVLIIHQRIHTGEKPYKCPECGKGFSNSSNFITHQRTHMKEKLY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	AADIPRVTTPLSSLV CCCCCCCCCCHHHHC	24.79	26074081
11	Phosphorylation	ADIPRVTTPLSSLVQ CCCCCCCCCHHHHCC	21.26	26074081
14	Phosphorylation	PRVTTPLSSLVQVPQ CCCCCCHHHHCCCCC	23.88	26074081
15	Phosphorylation	RVTTPLSSLVQVPQE CCCCCHHHHCCCCCH	40.00	26074081
161	Phosphorylation	NESRKIFSEMPEGES CHHHHHHHCCCCCCC	36.14	21406692
168	Phosphorylation	SEMPEGESAQHSDGE HCCCCCCCCCCCCCC	44.05	22115753
172	Phosphorylation	EGESAQHSDGESDFE CCCCCCCCCCCCHHH	34.92	22115753
176	Phosphorylation	AQHSDGESDFERDAG CCCCCCCCHHHHHHH	53.80	22115753
191	Phosphorylation	IQRLQGHSPGEDHGE HHHHCCCCCCCCCCE	41.23	29255136
234	Ubiquitination	CGKTFSRKSHLITHE CCCCCCCCCCEEEEC	40.82	-
243	Phosphorylation	HLITHERTHTGEKYY CEEEECCCCCCCCEE	22.32	-
245	Phosphorylation	ITHERTHTGEKYYKC EEECCCCCCCCEEEC	46.56	-
271	Phosphorylation	NFSRHQTTHTGEKPY CCCCCCCCCCCCCCE	15.74	28348404
273	Phosphorylation	SRHQTTHTGEKPYKC CCCCCCCCCCCCEEC	44.97	24719451
276	Ubiquitination	QTTHTGEKPYKCRDC CCCCCCCCCEECCCC	55.80	-
288	Phosphorylation	RDCGKSFSRSANLIT CCCCCCCCHHCCCCC	32.20	17081983
301	Phosphorylation	ITHQRIHTGEKPFQC CCCCCCCCCCCCEEH	44.67	-
316	Phosphorylation	AECGKSFSRSPNLIA HHCCCCCCCCCCEEE	38.65	27251275
318	Phosphorylation	CGKSFSRSPNLIAHQ CCCCCCCCCCEEEEC	19.55	30266825
327	Phosphorylation	NLIAHQRTHTGEKPY CEEEECCCCCCCCCC	19.74	-
329	Phosphorylation	IAHQRTHTGEKPYSC EEECCCCCCCCCCCC	46.56	-
357	Phosphorylation	NTHQGIHTGEKPYEC CCCCCCCCCCCCEEC	45.15	29496963
385	Phosphorylation	IRHQRIHTGEKPYKC CCCCCCCCCCCCEEC	44.67	29496963
411	Phosphorylation	ALITHRRTHTGEKPY CEEEECCCCCCCCCE	24.60	28111955
413	Phosphorylation	ITHRRTHTGEKPYQC EEECCCCCCCCCEEC	46.56	28111955
416	Sumoylation	RRTHTGEKPYQCSEC CCCCCCCCCEECCCC	50.82	-
416	Sumoylation	RRTHTGEKPYQCSEC CCCCCCCCCEECCCC	50.82	-
416	Ubiquitination	RRTHTGEKPYQCSEC CCCCCCCCCEECCCC	50.82	-
418	Phosphorylation	THTGEKPYQCSECGK CCCCCCCEECCCCCC	32.97	28111955
428	Phosphorylation	SECGKSFSRSSNLAT CCCCCCCCHHHCCHH	38.04	17081983
497	Phosphorylation	LKHQRIHTGEKPYKC HHCCCCCCCCCCEEC	44.67	29496963
523	Phosphorylation	QLVVHQRTHTGEKPY EEEEEECCCCCCCCE	19.74	28348404
525	Phosphorylation	VVHQRTHTGEKPYKC EEEECCCCCCCCEEE	46.56	26270265
528	Ubiquitination	QRTHTGEKPYKCLMC ECCCCCCCCEEEEEE	55.80	-
540	Phosphorylation	LMCGKSFSRGSILVM EEECCCCCCCCEEEE	42.71	17081983
581	Phosphorylation	IIHQRIHTGEKPYKC EEEEEECCCCCCCCC	44.67	29496963

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSCA2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSCA2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSCA2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZSCA2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.