dbPTM

ZSC23_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZSC23_HUMAN
UniProt AC	Q3MJ62
Protein Name	Zinc finger and SCAN domain-containing protein 23
Gene Name	ZSCAN23
Organism	Homo sapiens (Human).
Sequence Length	389
Subcellular Localization	Nucleus .
Protein Description	May be involved in transcriptional regulation..
Protein Sequence	MAITLTLQTAEMQEGLLAVKVKEEEEEHSCGPESGLSRNNPHTREIFRRRFRQFCYQESPGPREALQRLQELCHQWLRPEMHTKEQILELLVLEQFLTILPEELQAWVRQHRPVSGEEAVTVLEDLERELDDPGEQVLSHAHEQEEFVKEKATPGAAQESSNDQFQTLEEQLGYNLREVCPVQEIDGKAGTWNVELAPKREISQEVKSLIQVLGKQNGNITQIPEYGDTCDREGRLEKQRVSSSVERPYICSECGKSFTQNSILIEHQRTHTGEKPYECDECGRAFSQRSGLFQHQRLHTGEKRYQCSVCGKAFSQNAGLFHHLRIHTGEKPYQCNQCNKSFSRRSVLIKHQRIHTGERPYECEECGKNFIYHCNLIQHRKVHPVAESS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAITLTLQTAE ----CCEEEEEEHHH	12.26	24043423
6	Phosphorylation	--MAITLTLQTAEMQ --CCEEEEEEHHHHH	14.26	24043423
9	Phosphorylation	AITLTLQTAEMQEGL CEEEEEEHHHHHCCE	27.91	24043423
270	Phosphorylation	ILIEHQRTHTGEKPY EEEEECCCCCCCCCC	19.74	-
272	Phosphorylation	IEHQRTHTGEKPYEC EEECCCCCCCCCCCC	46.56	-
300	Phosphorylation	FQHQRLHTGEKRYQC CCCCCCCCCCCEEEE	52.18	21857030
303	2-Hydroxyisobutyrylation	QRLHTGEKRYQCSVC CCCCCCCCEEEEECC	58.72	-
328	Phosphorylation	FHHLRIHTGEKPYQC CCEEEEECCCCCCCC	44.67	28111955
343	Phosphorylation	NQCNKSFSRRSVLIK CCCCCCCCCCCEEEE	33.60	17081983
356	Phosphorylation	IKHQRIHTGERPYEC EEECEECCCCCCEEC	38.06	25690035

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZSC23_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZSC23_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZSC23_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ZSC23_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZSC23_HUMAN

Related Literatures of Post-Translational Modification