ZNF77_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF77_HUMAN
• UniProt AC: Q15935
• Protein Name: Zinc finger protein 77
• Gene Name: ZNF77
• Organism: Homo sapiens (Human).
• Sequence Length: 545
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MDCVIFEEVAVNFTPEEWALLDHAQRSLYRDVMLETCRNLASLDCYIYVRTSGSSSQRDVFGNGISNDEEIVKFTGSDSWSIFGENWRFDNTGDQHQIPQRHLRSQLGRLCESNEGHQCGETLSQTANLLVHKSYPTEAKPSECTKCGKAFENRQRSHTGQRPCKECGQACSCLSCQSPPMKTQTVEKPCNCQDSRTASVTYVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTHAGA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	Ubiquitination	SWSIFGENWRFDNTG CCEECCCCCEECCCC	35.29	22505724
114	Ubiquitination	LGRLCESNEGHQCGE HHHHHHCCCCCCCCC	36.66	22505724
204	Sumoylation	TASVTYVKSLSSKKS CEEEEEEEECCCCCC	34.95	-
204	Sumoylation	TASVTYVKSLSSKKS CEEEEEEEECCCCCC	34.95	-
253	Phosphorylation	GKTFMYYSYLTRHVR CCHHHHHHHHHHHHH	9.00	-
256	Phosphorylation	FMYYSYLTRHVRTHT HHHHHHHHHHHHHCC	15.53	-
261	Phosphorylation	YLTRHVRTHTGEKPY HHHHHHHHCCCCCCE	23.77	29396449
263	Phosphorylation	TRHVRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	29496963
266	Ubiquitination	VRTHTGEKPYECKEC HHHCCCCCCEECCCC	55.00	22505724
271	Acetylation	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	19811721
271	Sumoylation	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	-
271	Ubiquitination	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	-
271	Sumoylation	GEKPYECKECGKAFS CCCCEECCCCCCCCC	44.06	-
289	Phosphorylation	YFREHVRTHTGEKPY HHHHHHHHCCCCCCE	23.77	29396449
291	Phosphorylation	REHVRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	29496963
294	Ubiquitination	VRTHTGEKPYECKHC HHHCCCCCCEECCCC	55.00	22505724
304	Phosphorylation	ECKHCGKSFSCYSSF ECCCCCCEEEEEHHH	14.00	27135362
306	Phosphorylation	KHCGKSFSCYSSFRD CCCCCEEEEEHHHHH	21.16	27135362
317	Phosphorylation	SFRDHVRTHTGEKPC HHHHHHHHCCCCCCC	23.77	-
319	Phosphorylation	RDHVRTHTGEKPCQC HHHHHHCCCCCCCCC	46.56	-
334	Phosphorylation	KHCGKAFTCYSSLRE CCCCCEEEEHHHHHH	18.52	29978859
336	Phosphorylation	CGKAFTCYSSLREHG CCCEEEEHHHHHHHC	9.76	29978859
337	Phosphorylation	GKAFTCYSSLREHGR CCEEEEHHHHHHHCC	25.66	29978859
338	Phosphorylation	KAFTCYSSLREHGRT CEEEEHHHHHHHCCC	12.64	29978859
347	Phosphorylation	REHGRTHSGEKPYEC HHHCCCCCCCCCEEC	48.29	27251275
355	Sumoylation	GEKPYECKECGKAFR CCCCEECCCCCCCCC	44.06	-
355	Sumoylation	GEKPYECKECGKAFR CCCCEECCCCCCCCC	44.06	-
378	Sumoylation	MRMHTGEKPYVCKQC HHHHCCCCCEEECCC	42.89	-
378	Sumoylation	MRMHTGEKPYVCKQC HHHHCCCCCEEECCC	42.89	-
429	Phosphorylation	SLRIHVRTHTGEKPF CEEEEEEECCCCCCE	23.77	-
431	Phosphorylation	RIHVRTHTGEKPFEC EEEEEECCCCCCEEC	46.56	21857030
434	Ubiquitination	VRTHTGEKPFECKHC EEECCCCCCEECCCC	57.25	-
487	Phosphorylation	QKHVRSHSGVKPYEC HHHHHHCCCCCCEEE	46.67	25159151
523	Sumoylation	GERPYECKQCGKTFR CCCCEECCCCCCHHH	36.36	-
523	Sumoylation	GERPYECKQCGKTFR CCCCEECCCCCCHHH	36.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF77_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF77_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF77_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZNF77_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.