ZNF28_HUMAN - dbPTM
ZNF28_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZNF28_HUMAN
UniProt AC P17035
Protein Name Zinc finger protein 28
Gene Name ZNF28
Organism Homo sapiens (Human).
Sequence Length 718
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMKTFFSTGQGNTEAFHTGTLQRQASHHIGDFCFQKIEKDIHGFQFQWKEDETNDHAAPMTEIKELTGSTGQHDQRHAGNKHIKDQLGLSFHSHLPELHIFQPEGKIGNQVEKSINNASSVSTSQRICCRPKTHISNKYGNNSLHSSLLTQKRNVHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHIDEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNECGKTFSQMSNLVYHHRLHSGEKP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
18PhosphorylationRDVAIEFSQEEWKCL
HHHHHCCCHHHHHHC		24.7227251275
23UbiquitinationEFSQEEWKCLDPAQR
CCCHHHHHHCCHHHH		28.35-
41PhosphorylationRDVMLENYRNLVSLD
HHHHHHHHHHHEECC		7.4822210691
46PhosphorylationENYRNLVSLDISSKC
HHHHHHEECCCCCCH		24.4022210691
79PhosphorylationGTLQRQASHHIGDFC
HHHHHHHHHHHCHHH		13.7828555341
89SumoylationIGDFCFQKIEKDIHG
HCHHHHHHHHCCCCC		32.3628112733
113 (in isoform 2)Ubiquitination-4.5021906983
166UbiquitinationKIGNQVEKSINNASS
CHHHHHHHHHHCCCC		58.7529967540
167PhosphorylationIGNQVEKSINNASSV
HHHHHHHHHHCCCCC		19.6228555341
187 (in isoform 1)Ubiquitination-27.8321906983
191UbiquitinationPKTHISNKYGNNSLH
CCCCCCCCCCCCCHH		47.9829967540
203PhosphorylationSLHSSLLTQKRNVHM
CHHHHHHHHCCCCCC		37.02-
213UbiquitinationRNVHMREKSFQCIES
CCCCCCHHHHHHHHC		46.3229967540
222UbiquitinationFQCIESGKSFNCSSL
HHHHHCCCCCCHHHH		62.2429967540
223PhosphorylationQCIESGKSFNCSSLL
HHHHCCCCCCHHHHH		25.8029970186
228PhosphorylationGKSFNCSSLLKKHQI
CCCCCHHHHHHHHCC		39.6624719451
269SumoylationRRSHIDEKPYKCNEC
CCCCCCCCCEECCCC		50.31-
269SumoylationRRSHIDEKPYKCNEC
CCCCCCCCCEECCCC		50.31-
272SumoylationHIDEKPYKCNECGKI
CCCCCCEECCCCCCC		38.83-
272SumoylationHIDEKPYKCNECGKI
CCCCCCEECCCCCCC		38.83-
321PhosphorylationLETHKIIYTGGKPYK
HCCCEEEEECCCCCC		11.6429496907
327PhosphorylationIYTGGKPYKCKVCDK
EEECCCCCCCEECCC		32.29-
340PhosphorylationDKAFTCNSYLAKHTI
CCCEECCHHHHHCCE		24.5430631047
350PhosphorylationAKHTIIHTGEKPYKC
HHCCEEECCCCCEEC		36.3129496963
353UbiquitinationTIIHTGEKPYKCNEC
CEEECCCCCEECCCH		55.80-
355PhosphorylationIHTGEKPYKCNECGK
EECCCCCEECCCHHH		38.9618767875
356SumoylationHTGEKPYKCNECGKV
ECCCCCEECCCHHHH		38.83-
356SumoylationHTGEKPYKCNECGKV
ECCCCCEECCCHHHH		38.83-
368PhosphorylationGKVFNRLSTLARHRR
HHHHHHHHHHHHHCC		20.3824945436
378PhosphorylationARHRRLHTGEKPYEC
HHHCCCCCCCCCCCC		52.1821857030
406PhosphorylationERHKRIHTGEKPYKC
HHHCCCCCCCCCCCC		44.6729496963
411PhosphorylationIHTGEKPYKCKVCDK
CCCCCCCCCCCCCCC		39.83-
428SumoylationAYNSYLAKHSIIHTG
HCCHHHHHCCCEECC		34.9828112733
434PhosphorylationAKHSIIHTGEKPYKC
HHCCCEECCCCCEEC		36.3129496963
437SumoylationSIIHTGEKPYKCNEC
CCEECCCCCEECCCC		55.80-
437SumoylationSIIHTGEKPYKCNEC
CCEECCCCCEECCCC		55.80-
437UbiquitinationSIIHTGEKPYKCNEC
CCEECCCCCEECCCC		55.80-
439PhosphorylationIHTGEKPYKCNECGK
EECCCCCEECCCCCC		38.9618767875
440SumoylationHTGEKPYKCNECGKV
ECCCCCEECCCCCCC		38.83-
440SumoylationHTGEKPYKCNECGKV
ECCCCCEECCCCCCC		38.83-
468SumoylationHTAEKPYKCEECDKV
CCCCCCCCHHHCCCE		43.63-
468SumoylationHTAEKPYKCEECDKV
CCCCCCCCHHHCCCE		43.63-
480PhosphorylationDKVFRCKSHLERHRR
CCEEECHHHHHHHCC		36.6127282143
490PhosphorylationERHRRIHTGEKPYKC
HHHCCCCCCCCCCCC		44.6729496963
495PhosphorylationIHTGEKPYKCKVCDK
CCCCCCCCCCCCCCH		39.83-
502UbiquitinationYKCKVCDKAFRSDSC
CCCCCCCHHHCCCCC		44.27-
518PhosphorylationTEHQRVHTGEKPYMC
CCCCCHHCCCCCEEE		44.15-
534PhosphorylationECGKVFSTKANLACH
CCCCEEEHHHHHHHC		23.78-
574PhosphorylationERHRRIHTGEKPYKC
HHHHCCCCCCCCCCC		44.6729496963
579PhosphorylationIHTGEKPYKCKVCDK
CCCCCCCCCCCCCCH		39.83-
586UbiquitinationYKCKVCDKAFRRDSH
CCCCCCCHHHHCCHH		44.27-
602PhosphorylationAQHQRVHTGEKPYKC
HHHCCCCCCCCCEEC		44.1529496963
605SumoylationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
605SumoylationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
605UbiquitinationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
608SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
608UbiquitinationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
608SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
619UbiquitinationCGKTFRQTSSLIIHR
CCCCHHHCCEEEEEE		18.9421890473
630PhosphorylationIIHRRLHTGEKPYKC
EEEEECCCCCCCEEC		52.1827422710
633SumoylationRRLHTGEKPYKCNEC
EECCCCCCCEECCCC		55.80-
633UbiquitinationRRLHTGEKPYKCNEC
EECCCCCCCEECCCC		55.8021890473
633SumoylationRRLHTGEKPYKCNEC
EECCCCCCCEECCCC		55.80-
635PhosphorylationLHTGEKPYKCNECGK
CCCCCCCEECCCCCC		38.96-
636SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
636UbiquitinationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
636SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
658PhosphorylationVYHHRLHSGEKPYKC
HHHHCCCCCCCCEEC		53.9227794612
664SumoylationHSGEKPYKCNECGKV
CCCCCCEECCCHHHH		38.83-
664SumoylationHSGEKPYKCNECGKV
CCCCCCEECCCHHHH		38.83-
686PhosphorylationAQHQRVHTGEKPYKC
HHHCCCCCCCCCEEC		44.1529496963
689SumoylationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
689SumoylationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
689UbiquitinationQRVHTGEKPYKCNEC
CCCCCCCCCEECCCC		55.80-
692UbiquitinationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
692SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
692SumoylationHTGEKPYKCNECGKT
CCCCCCEECCCCCCC		38.83-
699PhosphorylationKCNECGKTFSQMSNL
ECCCCCCCHHHHHHH		17.5025404012
701PhosphorylationNECGKTFSQMSNLVY
CCCCCCHHHHHHHHH		30.1525404012
704PhosphorylationGKTFSQMSNLVYHHR
CCCHHHHHHHHHHHC		21.2625404012
708PhosphorylationSQMSNLVYHHRLHSG
HHHHHHHHHHCCCCC		8.6225404012
714PhosphorylationVYHHRLHSGEKP---
HHHHCCCCCCCC---		53.9225404012
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZNF28_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZNF28_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZNF28_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZNF28_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZNF28_HUMAN

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Related Literatures of Post-Translational Modification

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