ZNF25_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF25_HUMAN
• UniProt AC: P17030
• Protein Name: Zinc finger protein 25
• Gene Name: ZNF25
• Organism: Homo sapiens (Human).
• Sequence Length: 456
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRNGELTKHQKTHTTEKACECKECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	NKFQGPVTLKDVIVE CCCCCCCCHHHEEEE	31.09	24114839
33	Phosphorylation	TPAQRTLYKDVMLEN CHHHHHHHHHHHHHC	12.44	-
49	Phosphorylation	SHLVSVGYHVNKPNA CEEEEEEECCCCCCE	10.63	-
106	Phosphorylation	NSRNGELTKHQKTHT CCCCCCCCCCCCCCC	23.37	24719451
139	Phosphorylation	ALIVHQHTHSKGKSY EEEEEECCCCCCCCC	22.67	25627689
141	Phosphorylation	IVHQHTHSKGKSYDC EEEECCCCCCCCCCC	44.23	25627689
154	Phosphorylation	DCDKCGKSFSKNEDL CCCCCCCCCCCCHHH	21.75	24719451
220	Ubiquitination	QKPHLTEHQKTHTGE CCCCCCCCCCCCCCC	29.24	22505724
233	Phosphorylation	GEKPFECTECGKFFY CCCCEEECCCCCEEE	27.41	30576142
251	Phosphorylation	YLMVHQKTHTGEKPY EEEECCCCCCCCCCC	20.35	27251275
253	Phosphorylation	MVHQKTHTGEKPYEC EECCCCCCCCCCCCC	52.87	29496963
255	Ubiquitination	HQKTHTGEKPYECKE CCCCCCCCCCCCCCH	52.60	22505724
256	Ubiquitination	QKTHTGEKPYECKEC CCCCCCCCCCCCCHH	55.00	22505724
260	Ubiquitination	TGEKPYECKECGKAF CCCCCCCCCHHHCCH	3.57	22505724
261	Ubiquitination	GEKPYECKECGKAFS CCCCCCCCHHHCCHH	44.06	-
261	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHHCCHH	44.06	-
261	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHHCCHH	44.06	-
265	Acetylation	YECKECGKAFSQKSH CCCCHHHCCHHCCCC	58.90	20167786
271	Phosphorylation	GKAFSQKSHLTVHQR HCCHHCCCCCCHHHC	18.98	22617229
281	Phosphorylation	TVHQRMHTGEKPYKC CHHHCCCCCCCCCCC	37.38	22617229
284	Acetylation	QRMHTGEKPYKCKEC HCCCCCCCCCCCCCC	55.80	20167786
296	Phosphorylation	KECGKFFSRNSHLKT CCCCCCCCCCCCCCC	33.41	25394399
330	Phosphorylation	FYQKSALTVHQRTHT HEECCCEEEECCCCC	18.69	23532336
335	Phosphorylation	ALTVHQRTHTGEKPF CEEEECCCCCCCCCE	19.74	27251275
337	Phosphorylation	TVHQRTHTGEKPFEC EEECCCCCCCCCEEE	46.56	27251275
352	Phosphorylation	NKCGKTFYYKSDLTK CCCCCEEEECCCCCH	18.40	19562805
365	Phosphorylation	TKHQRKHTGEKPYEC CHHHHHHCCCCCEEE	50.50	23532336
391	Phosphorylation	VLRLHQRTHTGEKPY HHHHHHCCCCCCCCE	19.74	-
393	Phosphorylation	RLHQRTHTGEKPYAC HHHHCCCCCCCCEEC	46.56	-
396	Ubiquitination	QRTHTGEKPYACKEC HCCCCCCCCEECHHC	44.68	-
398	Phosphorylation	THTGEKPYACKECGK CCCCCCCEECHHCCC	35.38	26074081
421	Phosphorylation	IIHQRKHTGEKPYEC EEECCCCCCCCCCCC	50.50	23532336
439	O-linked_Glycosylation	GETFIQKSQLTAHQK HCEEEHHHHHHHHHH	17.66	29351928

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF25_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF25_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF25_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZNF25_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.