ZNF17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZNF17_HUMAN
• UniProt AC: P17021
• Protein Name: Zinc finger protein 17
• Gene Name: ZNF17
• Organism: Homo sapiens (Human).
• Sequence Length: 662
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MNLTEDYMVFEDVAIHFSQEEWGILNDVQRHLHSDVMLENFALLSSVGCWHGAKDEEAPSKQCVSVGVSQVTTLKPALSTQKAQPCETCSSLLKDILHLAEHDGTHPKRTAKLYLHQKEHLREKLTRSDEGRPSFVNDSVHLAKRNLTCMQGGKDFTGDSDLQQQALHSGWKPHRDTHGVEAFQSGQNNYSCTQCGKDFCHQHTLFEHQKIHTEERPYECSECGKLFRYNSDLIKHQRNHTGERPYKCSECGKAFSLKYNVVQHQKIHTGERPYECSECGKAFLRKSHLLQHQRIHTRPRPYVCSECGKAFLTQAHLVGHQKIHTGERPYGCNECGKYFMYSSALIRHQKVHTGERPFYCCECGKFFMDSCTLIIHQRVHTGEKPYECNECGKFFRYRSTLIRHQKVHTGEKPYECSECGKFFMDTSTLIIHQRVHTGEKPYECNKCGKFFRYCFTLNRHQRVHSGERPYECSECGKFFVDSCTLKSHQRVHTGERPFECSICGKSFRCRSTLDTHQRIHTGERPYECSECGKFFRHNSNHIRHRRNHFGERSFECTECGRVFSQNSHLIRHQKVHTRERTYKCSKCGKFFMDSSTLISHERVHTGEKPYECSECGKVFRYNSSLIKHRRIHTGERPYQCSECGRVFNQNSHLIQHQKVHTR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
91	Phosphorylation	QPCETCSSLLKDILH CCCHHHHHHHHHHHH	39.61	24719451
128	Phosphorylation	LREKLTRSDEGRPSF HHHHHCCCCCCCCCC	34.48	28555341
144	Ubiquitination	NDSVHLAKRNLTCMQ CCHHHHHHHCCEEEC	48.45	29967540
172	Ubiquitination	QALHSGWKPHRDTHG HHHHCCCCCCCCCCC	34.18	29967540
256	Phosphorylation	SECGKAFSLKYNVVQ CCCCCEEEEEEEEEE	28.89	24719451
269	Phosphorylation	VQHQKIHTGERPYEC EECCEECCCCCCCCC	44.18	-
338	Phosphorylation	GCNECGKYFMYSSAL CCCCCCCEEEEEHHH	4.47	25884760
341	Phosphorylation	ECGKYFMYSSALIRH CCCCEEEEEHHHCCC	6.92	25884760
353	Phosphorylation	IRHQKVHTGERPFYC CCCCCCCCCCCCEEE	43.66	28555341
381	Phosphorylation	IIHQRVHTGEKPYEC EEEEECCCCCCCEEC	44.15	28348404
384	Ubiquitination	QRVHTGEKPYECNEC EECCCCCCCEECCCC	55.00	-
393	Ubiquitination	YECNECGKFFRYRST EECCCCCCEEEECHH	53.65	-
393	Sumoylation	YECNECGKFFRYRST EECCCCCCEEEECHH	53.65	-
393	Sumoylation	YECNECGKFFRYRST EECCCCCCEEEECHH	53.65	-
409	Phosphorylation	IRHQKVHTGEKPYEC EECCCCCCCCCCEEC	50.45	28348404
437	Phosphorylation	IIHQRVHTGEKPYEC EEEEEEECCCCCEEC	44.15	-
521	Phosphorylation	DTHQRIHTGERPYEC CCCCCCCCCCCCEEC	38.06	-
533	Ubiquitination	YECSECGKFFRHNSN EECCCCCHHHCCCCC	53.65	-
594	Phosphorylation	CGKFFMDSSTLISHE CCCEEECCCCEEECC	17.27	-
605	Phosphorylation	ISHERVHTGEKPYEC EECCEECCCCCCEEC	44.15	28348404
621	Phosphorylation	ECGKVFRYNSSLIKH CCCCEEEECCCCCCC	14.13	-
624	Phosphorylation	KVFRYNSSLIKHRRI CEEEECCCCCCCCCC	30.40	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZNF17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZNF17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZNF17_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZNF17_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.