ZN891_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN891_HUMAN
• UniProt AC: A8MT65
• Protein Name: Zinc finger protein 891
• Gene Name: ZNF891
• Organism: Homo sapiens (Human).
• Sequence Length: 544
• Subcellular Localization: Nucleus.
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAVMDLSSPWALTKQDSACFHLRNAEEERMIAVFLTTWLQEPMTFKDVAVEFTQEEWMMLDSAQRSLYRDVMLENYRNLTSVEYQLYRLTVISPLDQEEIRNMKKRIPQAICPDQKIQPKTKESTVQKILWEEPSNAVKMIKLTMHNWSSTLREDWECHKIRKQHKIPGGHWRQMIYAPKKTVPQELFRDYHELEENSKLGSKLIFSQSIFTSKHCQKCYSEIGCLKHNSIINNYVKNSISEKLYESHECDTTLWHFQRNQTVQKEYTYSKHGMHFTHNMFPVPNNLHMAQNACECNKDETLCHQSSLKKQGQTHTEKKHECNQCGKAFKRISNLTLYKKSHMGEKQYECKECGKVFNDSSTLRRHVRTHTGEKPYECNQCGKAFSQKTSLKAHMRTHTGEKPYECNQCGKSFGTSSYLIVHKRIHTGEKLYECSECGKAFNTSSHLKVHKKIHTGENVYECSDCGKVFSGVSSLRMHIRTHTGEKPYECKECRKAFSVSSSLRRHVRIHTGEKPYECIQCGKAFSQSSSLIIHKRIHTERETL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MAVMDLSSPWALTKQ CCCCCCCCCCCCCCC	31.58	29116813
128	Ubiquitination	TKESTVQKILWEEPS CCCCHHHHHHHCCCC	35.12	29967540
144	Phosphorylation	AVKMIKLTMHNWSST HHHHEEEEECCCCHH	16.04	22798277
149	Phosphorylation	KLTMHNWSSTLREDW EEEECCCCHHHHHHH	20.82	22798277
150	Phosphorylation	LTMHNWSSTLREDWE EEECCCCHHHHHHHH	24.07	22798277
316	Phosphorylation	KKQGQTHTEKKHECN HHCCCCHHHHHHHHH	53.54	23532336
333	Phosphorylation	GKAFKRISNLTLYKK HHHHHHHHCCEEECC	29.80	28152594
336	Phosphorylation	FKRISNLTLYKKSHM HHHHHCCEEECCCCC	32.09	28152594
338	Phosphorylation	RISNLTLYKKSHMGE HHHCCEEECCCCCCC	15.90	28152594
341	Phosphorylation	NLTLYKKSHMGEKQY CCEEECCCCCCCCEE	17.98	28152594
369	Phosphorylation	TLRRHVRTHTGEKPY HHHHHHHHCCCCCCE	23.77	-
371	Phosphorylation	RRHVRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	23898821
374	Ubiquitination	VRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
374	Sumoylation	VRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
374	Sumoylation	VRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
397	Phosphorylation	SLKAHMRTHTGEKPY CHHHHHHHCCCCCCE	19.06	-
399	Phosphorylation	KAHMRTHTGEKPYEC HHHHHHCCCCCCEEC	46.56	-
402	Ubiquitination	MRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
402	Sumoylation	MRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
402	Sumoylation	MRTHTGEKPYECNQC HHHCCCCCCEECCCC	55.00	-
473	Phosphorylation	GKVFSGVSSLRMHIR CCEECCHHHEEEEEE	27.47	24719451
474	Phosphorylation	KVFSGVSSLRMHIRT CEECCHHHEEEEEEC	20.00	24719451
481	Phosphorylation	SLRMHIRTHTGEKPY HEEEEEECCCCCCCC	24.16	29396449
483	Phosphorylation	RMHIRTHTGEKPYEC EEEEECCCCCCCCCC	46.56	29496963
486	Ubiquitination	IRTHTGEKPYECKEC EECCCCCCCCCCHHH	55.00	22505724
498	Phosphorylation	KECRKAFSVSSSLRR HHHHHHHCCCHHHHH	26.42	22210691
500	Phosphorylation	CRKAFSVSSSLRRHV HHHHHCCCHHHHHHE	17.01	24670416
501	Phosphorylation	RKAFSVSSSLRRHVR HHHHCCCHHHHHHEE	31.10	24670416
502	Phosphorylation	KAFSVSSSLRRHVRI HHHCCCHHHHHHEEE	20.56	24670416
511	Phosphorylation	RRHVRIHTGEKPYEC HHHEEEECCCCCEEE	44.67	22210691
516	Phosphorylation	IHTGEKPYECIQCGK EECCCCCEEEEECCC	34.20	25022875
526	Phosphorylation	IQCGKAFSQSSSLII EECCCCCCCCCCEEE	33.73	25022875
528	Phosphorylation	CGKAFSQSSSLIIHK CCCCCCCCCCEEEEE	22.24	25022875
529	Phosphorylation	GKAFSQSSSLIIHKR CCCCCCCCCEEEEEE	22.87	25022875
530	Phosphorylation	KAFSQSSSLIIHKRI CCCCCCCCEEEEEEE	28.91	25022875

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN891_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN891_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN891_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN891_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.