ZN865_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN865_HUMAN
• UniProt AC: P0CJ78
• Protein Name: Zinc finger protein 865
• Gene Name: ZNF865
• Organism: Homo sapiens (Human).
• Sequence Length: 1059
• Subcellular Localization: Nucleus.
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEANPAGSGAGGGGSSGIGGEDGVHFQSYPFDFLEFLNHQRFEPMELYGEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPAGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENLGGPGAGAGTLAGKDA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Phosphorylation	PQPPPPQYDYPPQST CCCCCCCCCCCCCCC	24.18	-
93	Phosphorylation	KPKAEVPSSSSSSSS CCCCCCCCCCCCCCC	48.29	30576142
94	Phosphorylation	PKAEVPSSSSSSSSS CCCCCCCCCCCCCCC	28.33	-
95	Phosphorylation	KAEVPSSSSSSSSSS CCCCCCCCCCCCCCC	38.28	-
96	Phosphorylation	AEVPSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
97	Phosphorylation	EVPSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
98	Phosphorylation	VPSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
99	Phosphorylation	PSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	24275569
100	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
101	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
102	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	30576142
103	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	19664994
104	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	19664994
105	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	19664994
106	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	19664994
107	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	19664994
108	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
109	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
110	Phosphorylation	SSSSSSSSSSSSSSS CCCCCCCCCCCCCCC	35.87	-
111	Phosphorylation	SSSSSSSSSSSSSSQ CCCCCCCCCCCCCCC	35.87	-
113	Phosphorylation	SSSSSSSSSSSSQAK CCCCCCCCCCCCCCC	35.87	-
114	Phosphorylation	SSSSSSSSSSSQAKK CCCCCCCCCCCCCCC	35.87	-
116	Phosphorylation	SSSSSSSSSQAKKPD CCCCCCCCCCCCCCC	28.54	-
117	Phosphorylation	SSSSSSSSQAKKPDP CCCCCCCCCCCCCCC	35.78	-
164	Methylation	HLFGNLKRGGPASGP HHHCCCCCCCCCCCC	59.47	115920673
169	Phosphorylation	LKRGGPASGPGVTPG CCCCCCCCCCCCCCC	48.96	22210691
174	Phosphorylation	PASGPGVTPGLGAPA CCCCCCCCCCCCCCC	19.97	22210691
206	Phosphorylation	AAAACDPTKDDKGYF CHHHCCCCCCCCCHH	33.58	22210691
210	Ubiquitination	CDPTKDDKGYFRRLK CCCCCCCCCHHHHHH	66.69	29967540
210	Sumoylation	CDPTKDDKGYFRRLK CCCCCCCCCHHHHHH	66.69	-
210	Sumoylation	CDPTKDDKGYFRRLK CCCCCCCCCHHHHHH	66.69	-
247	Phosphorylation	VQHMLVHSGERPYEC HHHHHHCCCCCCEEC	34.56	22817900
265	Phosphorylation	GRTYNHVSSLIRHRR CCHHHHHHHHHHHCC	16.33	27080861
266	Phosphorylation	RTYNHVSSLIRHRRC CHHHHHHHHHHHCCC	27.08	24719451
361	Sumoylation	LCWKVFKKPSHLHQH CHHHHHCCCCHHCCC	40.04	-
361	Sumoylation	LCWKVFKKPSHLHQH CHHHHHCCCCHHCCC	40.04	-
373	Phosphorylation	HQHQIIHTGEKPFSC CCCCEEECCCCCCCC	36.31	27251275
398	Ubiquitination	ESLKRHVKTHSADLL HHHHHHHHHCCHHHH	34.10	29967540
399	Phosphorylation	SLKRHVKTHSADLLR HHHHHHHHCCHHHHC	21.70	26270265
401	Phosphorylation	KRHVKTHSADLLRLP HHHHHHCCHHHHCCC	28.80	25159151
420	Phosphorylation	GKAFRDASYLLKHQA CHHHHCHHHHHHHHH	22.17	24719451
421	Phosphorylation	KAFRDASYLLKHQAA HHHHCHHHHHHHHHH	20.13	24719451
455	Phosphorylation	KSYSAPQSLLRHKAA CCCCCCHHHHHHHHH	28.45	24719451
460	Ubiquitination	PQSLLRHKAAHAPPA CHHHHHHHHHCCCCH	40.61	29967540
573	Phosphorylation	KRHERIHTGEKPHQC HHHHHCCCCCCCCCC	44.67	-
601	Phosphorylation	SKHHVVHTRERPYKC CCCCEEECCCCCEEC	23.71	21406692
607	Sumoylation	HTRERPYKCELCGKV ECCCCCEECCCCCCH	24.74	-
607	Sumoylation	HTRERPYKCELCGKV ECCCCCEECCCCCCH	24.74	-
802	Sumoylation	ATCGQSFKHFLGLVT CCCCCHHHHHHHHHH	38.40	28112733
999	Ubiquitination	PACLKAFKDPGYFRK HHHHHHHCCCCHHHH	68.80	21890473
1020	Phosphorylation	GGRPFRCSSCGEGFA CCCCCCCCCCCCCCH	25.14	22210691
1021	Phosphorylation	GRPFRCSSCGEGFAN CCCCCCCCCCCCCHH	29.75	22210691
1029	Phosphorylation	CGEGFANTYGLKKHR CCCCCHHHHHHHHHH	18.61	22210691
1030	Phosphorylation	GEGFANTYGLKKHRL CCCCHHHHHHHHHHH	21.92	22210691
1040	Ubiquitination	KKHRLAHKAENLGGP HHHHHHHHHHHCCCC	52.36	29967540
1040	Sumoylation	KKHRLAHKAENLGGP HHHHHHHHHHHCCCC	52.36	28112733
1053	Phosphorylation	GPGAGAGTLAGKDA- CCCCCCCCCCCCCC-	16.95	24173317

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN865_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN865_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN865_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN865_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.