ZN845_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN845_HUMAN
• UniProt AC: Q96IR2
• Protein Name: Zinc finger protein 845
• Gene Name: ZNF845
• Organism: Homo sapiens (Human).
• Sequence Length: 970
• Subcellular Localization: Nucleus.
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMKEFSSTAQGNTEVIHTGTLQRHERHHIGDFCFQEMEKDIHDFEFQWKEDERNSHEAPMTEIKQLTGSTNRHDQRHAGNKPIKDQLGSSFHSHLPELHMFQTEGKIGNQVEKSINSASLVSTSQRISCRPKTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKKH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MALSQGLLTFR ----CCCCCCCEEHH	16.80	-
18	Phosphorylation	RDVAIEFSQEEWKCL HHHHHCCCHHHHHHC	24.72	27251275
23	Ubiquitination	EFSQEEWKCLDPAQR CCCHHHHHHCCHHHH	28.35	-
41	Phosphorylation	RDVMLENYRNLVSLD HHHHHHHHHHHEECC	7.48	22210691
46	Phosphorylation	ENYRNLVSLDISSKC HHHHHHEECCCCCCH	24.40	22210691
102	Ubiquitination	HDFEFQWKEDERNSH HHCCCCCCHHCCCCC	44.50	29967540
134	Ubiquitination	DQRHAGNKPIKDQLG CCCCCCCCCHHHHHH	47.40	-
142	Phosphorylation	PIKDQLGSSFHSHLP CHHHHHHHHHHHCCC	38.12	28555341
166	Ubiquitination	KIGNQVEKSINSASL CHHHHHHHHHHHHHH	58.75	29967540
190	Ubiquitination	RPKTHISKNYGNNFL CCCCCCCCCCCCCCC	54.29	29967540
200	Phosphorylation	GNNFLNSSLLTQKQE CCCCCCHHHHHHHHH	26.73	28555341
205	Sumoylation	NSSLLTQKQEVHMRE CHHHHHHHHHHHHHH	43.10	28112733
222	Ubiquitination	FQCNESGKAFNYSSV CCCCCCCCCCCHHHH	60.11	29967540
227	Phosphorylation	SGKAFNYSSVLRKHQ CCCCCCHHHHHHHHC	18.31	-
228	Phosphorylation	GKAFNYSSVLRKHQI CCCCCHHHHHHHHCE	18.14	-
241	Acetylation	QIIHLGAKQYKCDVC CEEEECCCEEECCCC	52.97	30593913
243	Phosphorylation	IHLGAKQYKCDVCGK EEECCCEEECCCCCC	16.93	-
279	Phosphorylation	KCNDCGKTFSQELTL CCCCCCCCCCEEEEE	17.50	28450419
281	Phosphorylation	NDCGKTFSQELTLTC CCCCCCCCEEEEEEE	28.16	28450419
294	Phosphorylation	TCHHRLHTGEKHYKC EEECCCCCCCCEEEC	52.18	21857030
350	Phosphorylation	VYHRRLHTGEKPYKC EEEEECCCCCCCCCC	52.18	27422710
353	Sumoylation	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	-
353	Ubiquitination	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	21890473
353	Sumoylation	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	-
356	Sumoylation	HTGEKPYKCEECDKA CCCCCCCCCCCCCCC	43.63	-
356	Sumoylation	HTGEKPYKCEECDKA CCCCCCCCCCCCCCC	43.63	-
365	Phosphorylation	EECDKAFSFKSNLER CCCCCCCCCHHHHHH	36.30	24719451
367	Sumoylation	CDKAFSFKSNLERHR CCCCCCCHHHHHHHH	36.92	-
367	Sumoylation	CDKAFSFKSNLERHR CCCCCCCHHHHHHHH	36.92	-
375	Ubiquitination	SNLERHRKIHTGEKP HHHHHHHCCCCCCCC	32.49	-
378	Phosphorylation	ERHRKIHTGEKPYKC HHHHCCCCCCCCCCC	50.97	29496963
406	Phosphorylation	TRHRRLHTGEKPYKC CCCCCCCCCCCCEEC	52.18	27422710
409	Sumoylation	RRLHTGEKPYKCNDC CCCCCCCCCEECCCC	55.80	-
409	Ubiquitination	RRLHTGEKPYKCNDC CCCCCCCCCEECCCC	55.80	21890473
409	Sumoylation	RRLHTGEKPYKCNDC CCCCCCCCCEECCCC	55.80	-
434	Phosphorylation	VYHRRLHTGEKPYKC HHHHHCCCCCCCCCC	52.18	27422710
437	Sumoylation	RRLHTGEKPYKCEEC HHCCCCCCCCCCCCC	55.80	-
437	Ubiquitination	RRLHTGEKPYKCEEC HHCCCCCCCCCCCCC	55.80	21890473
437	Sumoylation	RRLHTGEKPYKCEEC HHCCCCCCCCCCCCC	55.80	-
440	Sumoylation	HTGEKPYKCEECDEA CCCCCCCCCCCCCCC	43.63	-
440	Sumoylation	HTGEKPYKCEECDEA CCCCCCCCCCCCCCC	43.63	-
449	Phosphorylation	EECDEAFSFKSNLER CCCCCCCCCHHHHHH	38.52	24719451
451	Sumoylation	CDEAFSFKSNLERHR CCCCCCCHHHHHHHH	36.92	-
451	Sumoylation	CDEAFSFKSNLERHR CCCCCCCHHHHHHHH	36.92	-
462	Phosphorylation	ERHRRIHTGEKPYKC HHHHCCCCCCCCEEC	44.67	29496963
490	Phosphorylation	VYHRRLHTGEKPYKC EEEEECCCCCCCCCC	52.18	27422710
493	Sumoylation	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	-
493	Ubiquitination	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	21890473
493	Sumoylation	RRLHTGEKPYKCEEC EECCCCCCCCCCCCC	55.80	-
496	Sumoylation	HTGEKPYKCEECDEA CCCCCCCCCCCCCCC	43.63	-
496	Sumoylation	HTGEKPYKCEECDEA CCCCCCCCCCCCCCC	43.63	-
505	Phosphorylation	EECDEAFSFKSNLER CCCCCCCCCCCCHHH	38.52	24719451
507	Sumoylation	CDEAFSFKSNLERHR CCCCCCCCCCHHHCE	36.92	-
507	Sumoylation	CDEAFSFKSNLERHR CCCCCCCCCCHHHCE	36.92	-
518	Phosphorylation	ERHRIIHTGEKLYKC HHCEEEECCCEEEEC	36.31	27251275
523	Phosphorylation	IHTGEKLYKCNECGK EECCCEEEECCCCCC	25.27	-
530	Acetylation	YKCNECGKTFSRKSS EECCCCCCCCCCCCC	59.04	13467615
530	Ubiquitination	YKCNECGKTFSRKSS EECCCCCCCCCCCCC	59.04	-
535	Acetylation	CGKTFSRKSSLTRHC CCCCCCCCCCCCCCE	43.10	13467617
546	Phosphorylation	TRHCRLHTGEKPYQC CCCEEECCCCCCEEC	52.18	26055452
630	Phosphorylation	AVHWRTHSGEKPYKC EEEEECCCCCCCEEC	48.29	26425664
633	Ubiquitination	WRTHSGEKPYKCEEC EECCCCCCCEECCCC	58.11	-
636	Sumoylation	HSGEKPYKCEECDEA CCCCCCEECCCCCCC	43.63	-
636	Sumoylation	HSGEKPYKCEECDEA CCCCCCEECCCCCCC	43.63	-
645	Phosphorylation	EECDEAFSFKSNLQR CCCCCCCCCCHHHHH	38.52	24719451
658	Phosphorylation	QRHRRIHTGEKPYRC HHHCCCCCCCCCEEC	44.67	29496963
661	Sumoylation	RRIHTGEKPYRCNEC CCCCCCCCCEECCCC	49.01	-
661	Ubiquitination	RRIHTGEKPYRCNEC CCCCCCCCCEECCCC	49.01	-
661	Sumoylation	RRIHTGEKPYRCNEC CCCCCCCCCEECCCC	49.01	-
670	Ubiquitination	YRCNECGKTFSRKSY EECCCCCCCCCCCCC	59.04	-
676	Phosphorylation	GKTFSRKSYLTCHRR CCCCCCCCCEEECCC	25.02	27251275
686	Phosphorylation	TCHRRLHTGEKPYKC EECCCCCCCCCCEEC	52.18	27422710
689	Sumoylation	RRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
689	Ubiquitination	RRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	21890473
689	Sumoylation	RRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
691	Phosphorylation	LHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	-
692	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
692	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
692	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
714	Phosphorylation	IIHKAIHTGEKPYKC EEEEHHHCCCCCEEC	40.71	29496963
717	Sumoylation	KAIHTGEKPYKCNEC EHHHCCCCCEECCCC	55.80	-
717	Sumoylation	KAIHTGEKPYKCNEC EHHHCCCCCEECCCC	55.80	-
717	Ubiquitination	KAIHTGEKPYKCNEC EHHHCCCCCEECCCC	55.80	-
719	Phosphorylation	IHTGEKPYKCNECGK HHCCCCCEECCCCCC	38.96	18767875
720	Sumoylation	HTGEKPYKCNECGKA HCCCCCEECCCCCCC	38.83	-
720	Sumoylation	HTGEKPYKCNECGKA HCCCCCEECCCCCCC	38.83	-
729	Phosphorylation	NECGKAFSQKSSLTC CCCCCCCCCCCCCEE	41.37	-
731	Ubiquitination	CGKAFSQKSSLTCHL CCCCCCCCCCCEEEE	40.59	29967540
732	Phosphorylation	GKAFSQKSSLTCHLR CCCCCCCCCCEEEEE	23.96	-
733	Phosphorylation	KAFSQKSSLTCHLRL CCCCCCCCCEEEEEE	34.43	-
735	Phosphorylation	FSQKSSLTCHLRLHT CCCCCCCEEEEEEEC	10.38	-
742	Phosphorylation	TCHLRLHTGEKPYKC EEEEEEECCCCCCCC	52.18	27422710
745	Sumoylation	LRLHTGEKPYKCEEC EEEECCCCCCCCHHC	55.80	-
745	Ubiquitination	LRLHTGEKPYKCEEC EEEECCCCCCCCHHC	55.80	21890473
745	Sumoylation	LRLHTGEKPYKCEEC EEEECCCCCCCCHHC	55.80	-
748	Sumoylation	HTGEKPYKCEECDKV ECCCCCCCCHHCHHH	43.63	-
748	Sumoylation	HTGEKPYKCEECDKV ECCCCCCCCHHCHHH	43.63	-
770	Phosphorylation	EKHRRIHTGEKPYKC HHHHCCCCCCCCCCC	44.67	29496963
775	Phosphorylation	IHTGEKPYKCKVCDK CCCCCCCCCCCCCCH	39.83	-
788	Phosphorylation	DKAFGRDSHLAQHTR CHHHCCCCHHHHCCE	21.02	28555341
798	Phosphorylation	AQHTRIHTGEKPYKC HHCCEEECCCCCCCC	44.67	29496963
803	Phosphorylation	IHTGEKPYKCNECGK EECCCCCCCCCCCCC	38.96	18767875
804	Sumoylation	HTGEKPYKCNECGKN ECCCCCCCCCCCCCC	38.83	-
804	Sumoylation	HTGEKPYKCNECGKN ECCCCCCCCCCCCCC	38.83	-
826	Phosphorylation	VIHKAIHSGEKPYKC EEEHHHHCCCCCEEC	42.40	29496963
832	Sumoylation	HSGEKPYKCNECGKT HCCCCCEECCCCCCC	38.83	-
832	Sumoylation	HSGEKPYKCNECGKT HCCCCCEECCCCCCC	38.83	-
854	Phosphorylation	EIHKAIHTGEKPYKC HHHHHHHCCCCCEEC	40.71	29496963
857	Sumoylation	KAIHTGEKPYKCSEC HHHHCCCCCEECCCC	55.80	-
857	Sumoylation	KAIHTGEKPYKCSEC HHHHCCCCCEECCCC	55.80	-
857	Ubiquitination	KAIHTGEKPYKCSEC HHHHCCCCCEECCCC	55.80	-
882	Phosphorylation	SRHHRLHTGEKPYKC CCCCCCCCCCCCCCC	52.18	27422710
885	Sumoylation	HRLHTGEKPYKCNKC CCCCCCCCCCCCCCC	55.80	-
885	Ubiquitination	HRLHTGEKPYKCNKC CCCCCCCCCCCCCCC	55.80	21890473
885	Sumoylation	HRLHTGEKPYKCNKC CCCCCCCCCCCCCCC	55.80	-
910	Phosphorylation	ACHHRIHTGEKPYKC HHCCCCCCCCCCEEC	44.67	29496963
915	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	18767875
916	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
916	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
916	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
938	Phosphorylation	VIHKTIHTGEKPYKC EEEEEEECCCCCEEC	43.09	29496963
941	Sumoylation	KTIHTGEKPYKCNEC EEEECCCCCEECCCC	55.80	-
941	Sumoylation	KTIHTGEKPYKCNEC EEEECCCCCEECCCC	55.80	-
943	Phosphorylation	IHTGEKPYKCNECGK EECCCCCEECCCCHH	38.96	18767875
944	Sumoylation	HTGEKPYKCNECGKV ECCCCCEECCCCHHH	38.83	-
944	Sumoylation	HTGEKPYKCNECGKV ECCCCCEECCCCHHH	38.83	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN845_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN845_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN845_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN845_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.