ZN805_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN805_HUMAN
• UniProt AC: Q5CZA5
• Protein Name: Zinc finger protein 805
• Gene Name: ZNF805
• Organism: Homo sapiens (Human).
• Sequence Length: 627
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAMALTDPAQVSVTFDDVAVTFTQEEWGQLDLAQRTLYQEVMLENCGLLVSLGCPVPRPELIYHLEHGQEPWTRKEDLSQGTCPGDKGKPKSTEPTTCELALSEGISFWGQLTQGASGDSQLGQPKDQDGFSEMQGERLRPGLDSQKEKLPGKMSPKHDGLGTADSVCSRIIQDRVSLGDDVHDCDSHGSGKNPVIQEEENIFKCNECEKVFNKKRLLARHERIHSGVKPYECTECGKTFSKSTYLLQHHMVHTGEKPYKCMECGKAFNRKSHLTQHQRIHSGEKPYKCSECGKAFTHRSTFVLHNRSHTGEKPFVCKECGKAFRDRPGFIRHYIIHSGENPYECFECGKVFKHRSYLMWHQQTHTGEKPYECSECGKAFCESAALIHHYVIHTGEKPFECLECGKAFNHRSYLKRHQRIHTGEKPYVCSECGKAFTHCSTFILHKRAHTGEKPFECKECGKAFSNRADLIRHFSIHTGEKPYECMECGKAFNRRSGLTRHQRIHSGEKPYECIECGKTFCWSTNLIRHSIIHTGEKPYECSECGKAFSRSSSLTQHQRMHTGRNPISVTDVGRPFTSGQTSVNIQELLLGKNFLNVTTEENLLQEEASYMASDRTYQRETPQVSSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
96	Ubiquitination	KPKSTEPTTCELALS CCCCCCCCCHHHHHH	37.53	29967540
140	Dimethylation	EMQGERLRPGLDSQK HHHHCCCCCCCHHHH	29.48	-
140	Methylation	EMQGERLRPGLDSQK HHHHCCCCCCCHHHH	29.48	24379843
155	Phosphorylation	EKLPGKMSPKHDGLG HCCCCCCCCCCCCCC	33.99	23403867
177	Phosphorylation	RIIQDRVSLGDDVHD HHHHCCCCCCCCCCC	27.77	28555341
190	Phosphorylation	HDCDSHGSGKNPVIQ CCCCCCCCCCCCCCC	40.96	25849741
226	Phosphorylation	ARHERIHSGVKPYEC HHHHHHHCCCCCEEC	42.80	28348404
229	Ubiquitination	ERIHSGVKPYECTEC HHHHCCCCCEECCCC	45.46	29967540
231	Phosphorylation	IHSGVKPYECTECGK HHCCCCCEECCCCCC	20.23	15592455
254	Phosphorylation	LQHHMVHTGEKPYKC HHCCCCCCCCCCEEE	35.31	29496963
257	Ubiquitination	HMVHTGEKPYKCMEC CCCCCCCCCEEEHHC	55.80	-
257	Sumoylation	HMVHTGEKPYKCMEC CCCCCCCCCEEEHHC	55.80	-
257	Sumoylation	HMVHTGEKPYKCMEC CCCCCCCCCEEEHHC	55.80	-
259	Phosphorylation	VHTGEKPYKCMECGK CCCCCCCEEEHHCCC	28.08	-
282	Phosphorylation	TQHQRIHSGEKPYKC CCCCHHCCCCCCEEC	46.40	29496963
287	Phosphorylation	IHSGEKPYKCSECGK HCCCCCCEECCCCCC	35.38	22817900
290	Phosphorylation	GEKPYKCSECGKAFT CCCCEECCCCCCEEE	31.59	-
297	Phosphorylation	SECGKAFTHRSTFVL CCCCCEEECCCEEEE	22.65	-
310	Phosphorylation	VLHNRSHTGEKPFVC EEECCCCCCCCCEEE	48.56	-
313	Sumoylation	NRSHTGEKPFVCKEC CCCCCCCCCEEECCH	45.13	-
313	Ubiquitination	NRSHTGEKPFVCKEC CCCCCCCCCEEECCH	45.13	-
313	Sumoylation	NRSHTGEKPFVCKEC CCCCCCCCCEEECCH	45.13	-
318	Ubiquitination	GEKPFVCKECGKAFR CCCCEEECCHHHHHH	51.22	-
338	Phosphorylation	IRHYIIHSGENPYEC EEEEEEECCCCCEEC	37.08	21712546
366	Phosphorylation	MWHQQTHTGEKPYEC EEEECCCCCCCCEEC	50.88	23898821
369	Ubiquitination	QQTHTGEKPYECSEC ECCCCCCCCEECCHH	55.00	-
394	Phosphorylation	IHHYVIHTGEKPFEC HEEEEEECCCCCEEH	35.59	-
422	Phosphorylation	KRHQRIHTGEKPYVC HHHCCCCCCCCCEEE	44.67	28111955
425	Sumoylation	QRIHTGEKPYVCSEC CCCCCCCCCEEECCC	42.89	-
425	Sumoylation	QRIHTGEKPYVCSEC CCCCCCCCCEEECCC	42.89	-
450	Phosphorylation	ILHKRAHTGEKPFEC EECCCCCCCCCCCCC	46.16	29496963
453	Ubiquitination	KRAHTGEKPFECKEC CCCCCCCCCCCCCHH	57.25	-
453	Sumoylation	KRAHTGEKPFECKEC CCCCCCCCCCCCCHH	57.25	-
453	Sumoylation	KRAHTGEKPFECKEC CCCCCCCCCCCCCHH	57.25	-
458	Sumoylation	GEKPFECKECGKAFS CCCCCCCCHHHHHHC	49.17	-
458	Sumoylation	GEKPFECKECGKAFS CCCCCCCCHHHHHHC	49.17	-
458	Ubiquitination	GEKPFECKECGKAFS CCCCCCCCHHHHHHC	49.17	-
475	Phosphorylation	ADLIRHFSIHTGEKP HHHHHHCCCCCCCCC	13.82	-
478	Phosphorylation	IRHFSIHTGEKPYEC HHHCCCCCCCCCEEH	45.42	-
506	Phosphorylation	TRHQRIHSGEKPYEC CCCHHCCCCCCCEEE	46.40	28152594
511	Phosphorylation	IHSGEKPYECIECGK CCCCCCCEEEEECCC	34.20	28152594
534	Phosphorylation	IRHSIIHTGEKPYEC HCCCCEECCCCCEEC	36.31	29496963
537	Ubiquitination	SIIHTGEKPYECSEC CCEECCCCCEECCHH	55.00	-
539	Phosphorylation	IHTGEKPYECSECGK EECCCCCEECCHHCC	40.41	-
542	Phosphorylation	GEKPYECSECGKAFS CCCCEECCHHCCCCC	24.79	27251275
546	Ubiquitination	YECSECGKAFSRSSS EECCHHCCCCCCCCC	58.90	-
552	Phosphorylation	GKAFSRSSSLTQHQR CCCCCCCCCCHHHHH	28.40	27251275
553	Phosphorylation	KAFSRSSSLTQHQRM CCCCCCCCCHHHHHH	36.36	27251275
610	Phosphorylation	LLQEEASYMASDRTY HHHHHHHHHHCCCCC	12.07	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN805_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN805_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN805_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN805_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.