ZN773_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN773_HUMAN
• UniProt AC: Q6PK81
• Protein Name: Zinc finger protein 773
• Gene Name: ZNF773
• Organism: Homo sapiens (Human).
• Sequence Length: 442
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAAATLRDPAQQGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENFTLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAILRGSWQGAKAEAAAEQSASVEVPSSNVQQHQKQHCGEKPLKRQEGRVPVLRSCRVHLSEKSLQSREVGKDLLTSSGVLKHQVTHTGEKSHRSSKSREAFHAGKRHYKCSECGKAFGQKYLLVQHQRLHTGEKPYECSECGKLFSHKSNLFIHQIVHTGERPYGCSDCGKSFSRNADLIQHQRVHTGEKPFTCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKLFSFNSSLMKHQRVHTGERPYKCSECGKFYSHKSSLINHWRVHTGERPYECSECGKFFSQSSSLMQHRKVHTGEKPFKCNECGRFFSENSSLVKHQRVHTGAKPYECRECGKFFRHSSSLVKHRRIHTGEIQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
102	Phosphorylation	AEAAAEQSASVEVPS HHHHHHHHCCCCCCC	17.64	22210691
109	Phosphorylation	SASVEVPSSNVQQHQ HCCCCCCCCHHHHHH	39.46	22210691
110	Phosphorylation	ASVEVPSSNVQQHQK CCCCCCCCHHHHHHH	34.64	22210691
145	Ubiquitination	CRVHLSEKSLQSREV CEEECCHHHHHCCHH	53.76	-
158	Phosphorylation	EVGKDLLTSSGVLKH HHHHHHHHHHCCEEE	28.30	27251275
159	Phosphorylation	VGKDLLTSSGVLKHQ HHHHHHHHHCCEEEE	25.68	27251275
160	Phosphorylation	GKDLLTSSGVLKHQV HHHHHHHHCCEEEEE	27.90	27251275
174	Phosphorylation	VTHTGEKSHRSSKSR EEECCCCCCCCHHHH	21.60	-
177	Phosphorylation	TGEKSHRSSKSREAF CCCCCCCCHHHHHHH	36.37	-
180	Phosphorylation	KSHRSSKSREAFHAG CCCCCHHHHHHHHCC	36.98	-
202 (in isoform 2)	Ubiquitination	-	25.43	21890473
203	Sumoylation	CGKAFGQKYLLVQHQ HHHHHCCEEEEEEEC	37.94	-
203 (in isoform 1)	Ubiquitination	-	37.94	21890473
203	Ubiquitination	CGKAFGQKYLLVQHQ HHHHHCCEEEEEEEC	37.94	-
203	Sumoylation	CGKAFGQKYLLVQHQ HHHHHCCEEEEEEEC	37.94	-
214	Phosphorylation	VQHQRLHTGEKPYEC EEECEECCCCCCCCC	52.18	28152594
217	Ubiquitination	QRLHTGEKPYECSEC CEECCCCCCCCCCCC	55.00	-
219	Phosphorylation	LHTGEKPYECSECGK ECCCCCCCCCCCCCC	40.41	28152594
222	Phosphorylation	GEKPYECSECGKLFS CCCCCCCCCCCCCCC	24.79	28152594
242	Phosphorylation	FIHQIVHTGERPYGC EEEEEEECCCCCCCC	29.82	-
257	Phosphorylation	SDCGKSFSRNADLIQ CCCCCCCCCCCCCCC	31.54	17081983
270	Phosphorylation	IQHQRVHTGEKPFTC CCCCCCCCCCCCEEH	44.15	-
320	Ubiquitination	SFNSSLMKHQRVHTG ECCHHHHCCCCCCCC	41.71	-
326	Phosphorylation	MKHQRVHTGERPYKC HCCCCCCCCCCCEEC	37.57	27251275
342 (in isoform 2)	Ubiquitination	-	23.72	21890473
343 (in isoform 1)	Ubiquitination	-	35.48	21890473
343	Ubiquitination	CGKFYSHKSSLINHW CCCEECCCHHHCCCE	35.48	21890473
354	Phosphorylation	INHWRVHTGERPYEC CCCEEEECCCCCEEC	37.57	27251275
359	Phosphorylation	VHTGERPYECSECGK EECCCCCEECCHHHH	35.47	-
362	Phosphorylation	GERPYECSECGKFFS CCCCEECCHHHHHCC	24.79	27251275
382	Phosphorylation	MQHRKVHTGEKPFKC HHCCCCCCCCCCCCC	50.45	23898821
422	Ubiquitination	YECRECGKFFRHSSS CCHHHCCCCCCCCHH	53.65	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN773_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN773_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN773_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN773_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.