ZN761_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN761_HUMAN
• UniProt AC: Q86XN6
• Protein Name: Zinc finger protein 761
• Gene Name: ZNF761
• Organism: Homo sapiens (Human).
• Sequence Length: 746
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAFSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCTMKEFLSTAQGNREVFHAGTLQIHESHHNGDFCYQDVDKDIHDYEFQWQEDERNGHEAPMTKIKKLTGITERYDQSHARNKPIKDQLGSSFHSHLPEMHIFQTEEKIDNQVVKSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEKQV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	RDVAIEFSQEEWKCL HHHHHCCCHHHHHHC	24.72	27251275
23	Ubiquitination	EFSQEEWKCLDPAQR CCCHHHHHHCCHHHH	28.35	-
41	Phosphorylation	RDVMLENYRNLVSLD HHHHHHHHHHHEECC	7.48	22210691
46	Phosphorylation	ENYRNLVSLDISSKC HHHHHHEECCCCCCC	24.40	22210691
120	Phosphorylation	MTKIKKLTGITERYD CHHHHHHHCCCHHCC	37.66	20873877
122	Phosphorylation	KIKKLTGITERYDQS HHHHHHCCCHHCCCH	23.12	20873877
123	Phosphorylation	IKKLTGITERYDQSH HHHHHCCCHHCCCHH	26.31	20873877
126	Phosphorylation	LTGITERYDQSHARN HHCCCHHCCCHHHHC	16.47	20873877
129	Phosphorylation	ITERYDQSHARNKPI CCHHCCCHHHHCCCH	19.06	20873877
143	Phosphorylation	IKDQLGSSFHSHLPE HHHHHHHHHHHHCCC	25.77	28555341
167	Phosphorylation	IDNQVVKSVHDASLV HCHHHHHHHHHHHHH	17.34	-
172	Phosphorylation	VKSVHDASLVSTAQR HHHHHHHHHHHHHHH	35.05	-
175	Phosphorylation	VHDASLVSTAQRISC HHHHHHHHHHHHCCC	24.26	-
176	Phosphorylation	HDASLVSTAQRISCR HHHHHHHHHHHCCCC	21.23	-
185	Ubiquitination	QRISCRPKTHISNNH HHCCCCCCCCCCCCC	33.12	-
205	Sumoylation	NSSLLTQKQEVHMRE CHHHHHHHHHHHHHH	43.10	28112733
227	Phosphorylation	SGKAFNYSSLLRKHQ CCCCCCHHHHHHHHH	18.66	26434776
228	Phosphorylation	GKAFNYSSLLRKHQI CCCCCHHHHHHHHHH	22.51	24719451
265	Phosphorylation	ACHRRCHTGENPYKC CCCCCCCCCCCCEEC	50.22	-
271	Sumoylation	HTGENPYKCNECGKT CCCCCCEECCCCCCC	31.66	-
271	Sumoylation	HTGENPYKCNECGKT CCCCCCEECCCCCCC	31.66	-
278	Phosphorylation	KCNECGKTFSQTSSL ECCCCCCCCCCCCCC	17.50	-
282	Phosphorylation	CGKTFSQTSSLTCHR CCCCCCCCCCCEEEC	21.05	-
283	Phosphorylation	GKTFSQTSSLTCHRR CCCCCCCCCCEEECC	18.73	27251275
284	Phosphorylation	KTFSQTSSLTCHRRL CCCCCCCCCEEECCC	30.96	27251275
286	Phosphorylation	FSQTSSLTCHRRLHT CCCCCCCEEECCCCC	14.28	-
293	Phosphorylation	TCHRRLHTGEKPYKC EEECCCCCCCCCCCC	52.18	27422710
296	Sumoylation	RRLHTGEKPYKCEEC CCCCCCCCCCCCCCC	55.80	-
296	Ubiquitination	RRLHTGEKPYKCEEC CCCCCCCCCCCCCCC	55.80	-
296	Sumoylation	RRLHTGEKPYKCEEC CCCCCCCCCCCCCCC	55.80	-
296 (in isoform 1)	Ubiquitination	-	55.80	21890473
299	Sumoylation	HTGEKPYKCEECDKA CCCCCCCCCCCCCCC	43.63	-
299	Sumoylation	HTGEKPYKCEECDKA CCCCCCCCCCCCCCC	43.63	-
324	Sumoylation	RIIHTEEKPYKCNEC CCEECCCCCCCCCCC	47.63	-
324	Sumoylation	RIIHTEEKPYKCNEC CCEECCCCCCCCCCC	47.63	-
327	Sumoylation	HTEEKPYKCNECGKT ECCCCCCCCCCCCCC	38.83	-
327	Sumoylation	HTEEKPYKCNECGKT ECCCCCCCCCCCCCC	38.83	-
334	Phosphorylation	KCNECGKTFRQKSIL CCCCCCCCHHHHHHH	14.88	-
339	Phosphorylation	GKTFRQKSILTRHHR CCCHHHHHHHHHHCC	17.94	24719451
342	Phosphorylation	FRQKSILTRHHRLHT HHHHHHHHHHCCCCC	26.70	20860994
349	Phosphorylation	TRHHRLHTGEKPYKC HHHCCCCCCCCCEEC	52.18	27422710
352	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
352	Ubiquitination	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
352	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
354	Phosphorylation	LHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	-
355	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
355	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
355	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
377	Phosphorylation	TCHHRLHTGEKPYKC EECCCCCCCCCCEEC	52.18	27422710
380	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
380	Ubiquitination	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
380	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
382	Phosphorylation	LHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	-
383	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
383	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
383	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
405	Phosphorylation	TCHRRLHTGEKPYKC EEEHHCCCCCCCEEC	52.18	27422710
408	Sumoylation	RRLHTGEKPYKCEEC HHCCCCCCCEECCCC	55.80	-
408	Ubiquitination	RRLHTGEKPYKCEEC HHCCCCCCCEECCCC	55.80	-
408	Sumoylation	RRLHTGEKPYKCEEC HHCCCCCCCEECCCC	55.80	-
411	Sumoylation	HTGEKPYKCEECDKA CCCCCCEECCCCCCC	43.63	-
411	Sumoylation	HTGEKPYKCEECDKA CCCCCCEECCCCCCC	43.63	-
445	Ubiquitination	YKCNECGKTFSRTSS EECCCCCCEEECCCC	59.04	-
450	Phosphorylation	CGKTFSRTSSLTCHR CCCEEECCCCCEEEC	22.82	-
451	Phosphorylation	GKTFSRTSSLTCHRR CCEEECCCCCEEECC	23.41	27251275
452	Phosphorylation	KTFSRTSSLTCHRRR CEEECCCCCEEECCC	27.38	27251275
454	Phosphorylation	FSRTSSLTCHRRRHT EECCCCCEEECCCCC	14.28	-
467	Sumoylation	HTGEQPYKCEECDKA CCCCCCEECHHCCCC	41.68	-
467	Sumoylation	HTGEQPYKCEECDKA CCCCCCEECHHCCCC	41.68	-
489	Phosphorylation	ERHRRIHTGEKPYKC HHHHCCCCCCCCEEC	44.67	29496963
494	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	18767875
495	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
495	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
495	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
501	Ubiquitination	YKCNECGKTFSRKSY EECCCCCCCCCCCCC	59.04	-
507	Phosphorylation	GKTFSRKSYLTCHHR CCCCCCCCCCEECCC	25.02	29507054
517	Phosphorylation	TCHHRLHTGEKAYKC EECCCCCCCCCEEEC	52.18	21857030
545	Phosphorylation	TCHRRLHSGEKPYKC EEHHHCCCCCCCEEC	53.92	27794612
558	Phosphorylation	KCKECGKTFNQQLTL ECCCCCCCHHHHHHH	17.07	23403867
566	Ubiquitination	FNQQLTLKRHRRLHS HHHHHHHHHHHHCCC	40.71	-
573	Phosphorylation	KRHRRLHSGENPYKC HHHHHCCCCCCCCCC	53.01	28555341
588	Phosphorylation	EDSDKAYSFKSNLEI CCCCCCEECCCCHHH	30.93	24719451
607	Sumoylation	HTEENPYKCNECGKT CCCCCCCCCCCCCCC	31.66	-
613	Ubiquitination	YKCNECGKTFSRTSS CCCCCCCCCCCCCCC	59.04	-
618	Phosphorylation	CGKTFSRTSSLTCHR CCCCCCCCCCCEEEC	22.82	-
619	Phosphorylation	GKTFSRTSSLTCHRR CCCCCCCCCCEEECC	23.41	27251275
620	Phosphorylation	KTFSRTSSLTCHRRL CCCCCCCCCEEECCC	27.38	27251275
622	Phosphorylation	FSRTSSLTCHRRLHT CCCCCCCEEECCCCC	14.28	-
629	Phosphorylation	TCHRRLHTGEKPYKC EEECCCCCCCCCEEC	52.18	27422710
632	Sumoylation	RRLHTGEKPYKCEEC CCCCCCCCCEECCCC	55.80	-
632	Ubiquitination	RRLHTGEKPYKCEEC CCCCCCCCCEECCCC	55.80	-
632	Sumoylation	RRLHTGEKPYKCEEC CCCCCCCCCEECCCC	55.80	-
635	Sumoylation	HTGEKPYKCEECDKA CCCCCCEECCCCCCE	43.63	-
635	Sumoylation	HTGEKPYKCEECDKA CCCCCCEECCCCCCE	43.63	-
657	Phosphorylation	EGHRRIHTGEKPYKC CCCCCCCCCCCCEEC	44.67	29496963
662	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	18767875
663	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
663	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
663	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
669	Ubiquitination	YKCNECGKTFSRKSY EECCCCCCCCCCCEE	59.04	-
685	Phosphorylation	ICHHRLHTGEKPYKC EEECCCCCCCCCCCC	52.18	27422710
685	Phosphorylation	ICHHRLHTGEKPYKC EEECCCCCCCCCCCC	52.18	-
688	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCCCCCCC	55.80	-
688	Ubiquitination	HRLHTGEKPYKCNEC CCCCCCCCCCCCCCC	55.80	-
688	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCCCCCCC	55.80	-
690	Phosphorylation	LHTGEKPYKCNECGK CCCCCCCCCCCCCCC	38.96	-
691	Sumoylation	HTGEKPYKCNECGKN CCCCCCCCCCCCCCC	38.83	-
691	Ubiquitination	HTGEKPYKCNECGKN CCCCCCCCCCCCCCC	38.83	-
691	Sumoylation	HTGEKPYKCNECGKN CCCCCCCCCCCCCCC	38.83	-
713	Phosphorylation	ICHHRLHTGEKPYKC EECCCCCCCCCCEEC	52.18	27422710
716	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
716	Ubiquitination	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
716	Sumoylation	HRLHTGEKPYKCNEC CCCCCCCCCEECCCC	55.80	-
718	Phosphorylation	LHTGEKPYKCNECGK CCCCCCCEECCCCCC	38.96	-
719	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
719	Ubiquitination	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
719	Sumoylation	HTGEKPYKCNECGKT CCCCCCEECCCCCCC	38.83	-
741	Phosphorylation	TCHRRLHTGEKQV-- EEEEECCCCCCCC--	52.18	21857030

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN761_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN761_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN761_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN761_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.