ZN721_HUMAN - dbPTM
ZN721_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN721_HUMAN
UniProt AC Q8TF20
Protein Name Zinc finger protein 721
Gene Name ZNF721
Organism Homo sapiens (Human).
Sequence Length 911
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MCSHFTQDFLPVQGIEDSFHKLILRRYEKCGHDNLQLRKGCKSMNVCKVQKGVYNGINKCLSNTQSKIFQCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIHTGDKTIQV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
54PhosphorylationCKVQKGVYNGINKCL
CHHHCCHHCCHHHHH		19.1519690332
62PhosphorylationNGINKCLSNTQSKIF
CCHHHHHHCCCHHHH		47.5029083192
64PhosphorylationINKCLSNTQSKIFQC
HHHHHHCCCHHHHCC		30.7329083192
66PhosphorylationKCLSNTQSKIFQCNA
HHHHCCCHHHHCCCH		26.1929083192
92UbiquitinationNKDKTRHTGEKHFKC
CCCCCCCCCCCCEEE		43.6929967540
92PhosphorylationNKDKTRHTGEKHFKC
CCCCCCCCCCCCEEE		43.6923532336
132SumoylationYTCEERGKDFGWYTD
EEHHHCCCCCCCCCC		56.98-
135UbiquitinationEERGKDFGWYTDLNQ
HHCCCCCCCCCCHHH		26.9829967540
137PhosphorylationRGKDFGWYTDLNQHK
CCCCCCCCCCHHHCC		7.25-
144UbiquitinationYTDLNQHKKIHTGEK
CCCHHHCCCCCCCCC		43.5929967540
148PhosphorylationNQHKKIHTGEKPYKC
HHCCCCCCCCCCEEH		50.9729496963
153PhosphorylationIHTGEKPYKCEECGK
CCCCCCCEEHHHHHH		39.06-
154SumoylationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHH		43.63-
154UbiquitinationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHH		43.63-
194PhosphorylationDRAFGWSTNLNEYKK
HHCCCCCCCHHHHHC		36.90-
199PhosphorylationWSTNLNEYKKIHTGD
CCCCHHHHHCCCCCC		19.26-
204PhosphorylationNEYKKIHTGDKPYKC
HHHHCCCCCCCCCCC		51.0224719451
232PhosphorylationNKHEKIHTGEKPYKC
CCCCCCCCCCCCCCC		50.9729496963
237PhosphorylationIHTGEKPYKCKECGK
CCCCCCCCCCCCCCC		39.83-
249PhosphorylationCGKVISSSSSFAKHK
CCCEECCCCHHHHCC		24.18-
250PhosphorylationGKVISSSSSFAKHKR
CCEECCCCHHHHCCC		31.27-
251PhosphorylationKVISSSSSFAKHKRI
CEECCCCHHHHCCCC		31.04-
260PhosphorylationAKHKRIHTGEKPFKC
HHCCCCCCCCCCEEE		44.6718669648
266SumoylationHTGEKPFKCLECGKA
CCCCCCEEEECCCCE		46.57-
266UbiquitinationHTGEKPFKCLECGKA
CCCCCCEEEECCCCE		46.5729967540
278UbiquitinationGKAFNISTTLTKHRR
CCEEEEECCEECCCC		23.2521890473
288PhosphorylationTKHRRIHTGEKPYTC
ECCCCCCCCCCCEEE		44.6729083192
293PhosphorylationIHTGEKPYTCEVCGK
CCCCCCCEEEEECHH		34.7818083107
316PhosphorylationYVHRRIHTGEKPYTC
EEECCCCCCCCCEEC		44.6728111955
319UbiquitinationRRIHTGEKPYTCGEC
CCCCCCCCCEECCCC		44.67-
344PhosphorylationYVHRRIHTGEKPYKC
EEEEEECCCCCCEEC		44.6729496963
347UbiquitinationRRIHTGEKPYKCEDC
EEECCCCCCEECCCH		55.80-
350SumoylationHTGEKPYKCEDCGKA
CCCCCCEECCCHHHH		39.41-
350UbiquitinationHTGEKPYKCEDCGKA
CCCCCCEECCCHHHH		39.41-
372PhosphorylationNQHKKIHTGEKPYKC
HCCCCCCCCCCCEEH		50.9729496963
377PhosphorylationIHTGEKPYKCEECGK
CCCCCCCEEHHHHHH		39.06-
378SumoylationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHC		43.63-
378UbiquitinationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHC		43.63-
390PhosphorylationGKAFNSSTNLTAHKR
HHCCCCCCCCCCCCC		33.7824114839
393PhosphorylationFNSSTNLTAHKRIHT
CCCCCCCCCCCCCCC		28.8724114839
428PhosphorylationNEYKKIHTGDKPYKC
HHCCCCCCCCCCCCC		51.0224719451
478SumoylationTSSSSFAKHKRIHTG
ECCCHHHHCCCCCCC		47.88-
478SumoylationTSSSSFAKHKRIHTG
ECCCHHHHCCCCCCC		47.8828112733
490UbiquitinationHTGEKPFECLECGKA
CCCCCCEEEECCCCE		46.8829967540
499PhosphorylationLECGKAFTSSTTLTK
ECCCCEECCCCCEEE		26.99-
501PhosphorylationCGKAFTSSTTLTKHR
CCCEECCCCCEEECC		23.50-
502PhosphorylationGKAFTSSTTLTKHRR
CCEECCCCCEEECCC		26.1219413330
505PhosphorylationFTSSTTLTKHRRIHT
ECCCCCEEECCCCCC		23.7827762562
512PhosphorylationTKHRRIHTGEKPYTC
EECCCCCCCCCCEEE		44.6729083192
517PhosphorylationIHTGEKPYTCEVCGK
CCCCCCCEEEEECCH		34.7818083107
527MethylationEVCGKAFRQSAILYV
EECCHHHHHHEEEEE		34.1124384611
540PhosphorylationYVHRRIHTGEKPYTC
EEEEECCCCCCCEEH		44.6728111955
568PhosphorylationYVHRRIHTGEKPYKC
EEEEEECCCCCCEEH		44.6729496963
573PhosphorylationIHTGEKPYKCEECGK
ECCCCCCEEHHHHHH		39.06-
574UbiquitinationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHH		43.63-
574SumoylationHTGEKPYKCEECGKA
CCCCCCEEHHHHHHH		43.63-
585PhosphorylationCGKAFGRYTDLNQHK
HHHHHCCCCCHHHCC		12.65-
596PhosphorylationNQHKKIHTGEKLYKC
HHCCCCCCCCCEEEC		50.97-
601PhosphorylationIHTGEKLYKCEECGK
CCCCCCEEECCHHCC		25.35-
602SumoylationHTGEKLYKCEECGKD
CCCCCEEECCHHCCC		45.68-
623PhosphorylationLNQQKKIYTGEKPYK
CCCCCCEECCCCCEE		19.99-
629PhosphorylationIYTGEKPYKCEECGK
EECCCCCEECCCCCC		39.06-
630SumoylationYTGEKPYKCEECGKA
ECCCCCEECCCCCCE		43.63-
649SumoylationTDLNQHTKILTGEQS
CCCCCCCCCCCCCCE		33.3328112733
658UbiquitinationLTGEQSYKCEECGKA
CCCCCEEECHHHHHH		40.18-
658SumoylationLTGEQSYKCEECGKA
CCCCCEEECHHHHHH		40.18-
680PhosphorylationNQHKKIHTGEKPYKC
CCCCCCCCCCCCEEC		50.9729496963
685PhosphorylationIHTGEKPYKCEECGK
CCCCCCCEECHHHHH		39.06-
686UbiquitinationHTGEKPYKCEECGKA
CCCCCCEECHHHHHH		43.63-
686SumoylationHTGEKPYKCEECGKA
CCCCCCEECHHHHHH		43.63-
721PhosphorylationKCEDRGRSFGWSTNL
ECCCCCCCCCCCCCH		30.8225332170
731PhosphorylationWSTNLNEYKKIHTGD
CCCCHHHCCCCCCCC		19.26-
736PhosphorylationNEYKKIHTGDKLYKC
HHCCCCCCCCCEEEH		51.0225332170
744UbiquitinationGDKLYKCKECGKVFK
CCCEEEHHHHHHHHH		52.4629967540
763UbiquitinationLNRHEKIHTGKKPYK
CCCCCCCCCCCCCCC		39.3729967540
786SumoylationTSSSSFAKHKRIHTG
ECCCHHHCCCCCCCC		47.8828112733
786SumoylationTSSSSFAKHKRIHTG
ECCCHHHCCCCCCCC		47.88-
792PhosphorylationAKHKRIHTGEKPFKC
HCCCCCCCCCCCEEE		44.6718669648
798UbiquitinationHTGEKPFKCLECGKA
CCCCCCEEEECCCCE		46.57-
798SumoylationHTGEKPFKCLECGKA
CCCCCCEEEECCCCE		46.57-
807PhosphorylationLECGKAFTSSTTLTK
ECCCCEECCCCCCEE		26.99-
809PhosphorylationCGKAFTSSTTLTKHR
CCCEECCCCCCEECC		23.50-
810UbiquitinationGKAFTSSTTLTKHRR
CCEECCCCCCEECCC		26.1221890473
810PhosphorylationGKAFTSSTTLTKHRR
CCEECCCCCCEECCC		26.1219413330
820PhosphorylationTKHRRIHTGEKPYTC
EECCCCCCCCCCCCH		44.6728111955
835MethylationEECGKAFRQSAILYV
HHHHHHHHHHHHHEE		34.1124384617
848PhosphorylationYVHRRIHTGEKPYTC
EEECCCCCCCCCEEC		44.6728111955
876PhosphorylationYAHKKIHTGEKPYTC
EEECEECCCCCCEEC		50.97-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN721_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN721_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN721_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZN721_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN721_HUMAN

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Related Literatures of Post-Translational Modification

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