ZN691_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN691_HUMAN
• UniProt AC: Q5VV52
• Protein Name: Zinc finger protein 691
• Gene Name: ZNF691
• Organism: Homo sapiens (Human).
• Sequence Length: 312
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSLCSPTHSAEMSLFLQGPEEMLPLSSEGSEMGSEKEQSPEPHLPEEGEGGKPWRVDDSEGSWIPPGEKEHGQESLSDELQETHPKKPWQKVTVRARELGDPIAHPRHEADEKPFICAQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYKCPKCQESFRRRSDLTTHQQDHLGKRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTVCGKHFSRSSNLKPFIPLWRMVLYSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MSLCSPTHSA -----CCCCCCCCCC	3.02	24719451
3 (in isoform 2)	Phosphorylation	-	3.02	26425664
8	Phosphorylation	MSLCSPTHSAEMSLF CCCCCCCCCCCEEHH	28.53	24719451
8 (in isoform 2)	Phosphorylation	-	28.53	25849741
34	Phosphorylation	SEGSEMGSEKEQSPE CCCCCCCCCCCCCCC	44.15	23663014
39	Phosphorylation	MGSEKEQSPEPHLPE CCCCCCCCCCCCCCC	32.11	23401153
39 (in isoform 3)	Phosphorylation	-	32.11	27251275
44	Phosphorylation	EQSPEPHLPEEGEGG CCCCCCCCCCCCCCC	9.27	-
75	Phosphorylation	EKEHGQESLSDELQE CHHCCCCCCCHHHHH	25.86	29255136
75 (in isoform 3)	Phosphorylation	-	25.86	27251275
77	Phosphorylation	EHGQESLSDELQETH HCCCCCCCHHHHHHC	38.01	29255136
77 (in isoform 3)	Phosphorylation	-	38.01	27251275
83	Phosphorylation	LSDELQETHPKKPWQ CCHHHHHHCCCCCCC	30.44	23403867
113	Sumoylation	PRHEADEKPFICAQC CCCCCCCCCEEEEEC	45.86	28112733
113	Sumoylation	PRHEADEKPFICAQC CCCCCCCCCEEEEEC	45.86	-
138	Phosphorylation	RTHQRIHTGEKPYKC CCCCEEECCCCCEEC	44.67	29496963
153	Phosphorylation	SECGKSFSRSSNRIR CCCCCCCCCCCCCCC	38.04	17081983
184	Phosphorylation	QESFRRRSDLTTHQQ HHHHHHHHHCCHHHH	34.85	20873877
187	Phosphorylation	FRRRSDLTTHQQDHL HHHHHHCCHHHHHCC	27.50	28348404
188	Phosphorylation	RRRSDLTTHQQDHLG HHHHHCCHHHHHCCC	25.61	28348404
196	Acetylation	HQQDHLGKRPYRCDI HHHHCCCCCCEECCC	57.47	25953088
207	Phosphorylation	RCDICGKSFSQSATL ECCCCCCCCCCCCEE	18.53	24425749
235	Phosphorylation	ICCECGKSFSNSSSF EEECCCCCCCCCCCC	21.13	28555341
237	Phosphorylation	CECGKSFSNSSSFGV ECCCCCCCCCCCCCC	42.78	28555341
239	Phosphorylation	CGKSFSNSSSFGVHH CCCCCCCCCCCCCCC	26.59	28555341
240	Phosphorylation	GKSFSNSSSFGVHHR CCCCCCCCCCCCCCC	33.66	28555341
250	Phosphorylation	GVHHRTHTGERPYEC CCCCCCCCCCCCEEE	39.87	25159151
265 (in isoform 2)	Phosphorylation	-	33.16	-
273 (in isoform 2)	Phosphorylation	-	20.31	28985074
283 (in isoform 2)	Phosphorylation	-	29.41	25159151
283	Phosphorylation	THRGEKPYRCTVCGK CCCCCCCEEEEECCC	29.41	24719451
284 (in isoform 2)	Phosphorylation	-	20.39	25159151
284	Phosphorylation	HRGEKPYRCTVCGKH CCCCCCEEEEECCCC	20.39	-
296 (in isoform 3)	Phosphorylation	-	45.10	-
304 (in isoform 3)	Phosphorylation	-	3.76	28985074
314 (in isoform 3)	Phosphorylation	-		25159151
315 (in isoform 3)	Phosphorylation	-		25159151
315	Phosphorylation	VLYSL---------- HHHCC----------		20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN691_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN691_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN691_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HAP1_HUMAN	HAP1	physical	16169070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.