ZN687_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN687_MOUSE
• UniProt AC: Q9D2D7
• Protein Name: Zinc finger protein 687
• Gene Name: Znf687
• Organism: Mus musculus (Mouse).
• Sequence Length: 1237
• Subcellular Localization: Cytoplasm . Nucleus . Predominantly nuclear.
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPEPSVGGDSKDREEAAAAENDPESPAEASDHGLPQPPDTSTVSVIVKNTVCPEQSESLTGDSGEEETKAGGITKEGPVGSCLMQNGFGGPEPSLSENPHSSAHASGNAWKDKAVEGKTCLDLFAHFGSEPGDHPDPLPPEPSQPRGGDMAPPPFSTPFELAPENGSTLLPPASLLPQGALKQESCSPHHSQGLTQRGPGSSPETAGIPASVSPPQVAGVSFKQSPGHQSPPASPVKAPSCKPLKEEDEGTVDKSPPRSPQSPSSGAEAADEDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAETSFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKSVLGLVPQTLPKAEVRTGFSLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPTASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRAPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNSIKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAVGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSSSEEELPSSPEPPRPTKRARRGELGNKGIKGGGGGPGGWTCGLCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLARGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGPLRYRSSGSAEQSLVGLRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEAAPPLRSDPEGGDSPLPAPGDPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MGDMKTPDFDDLL --CCCCCCCCHHHHH	22.81	21743459
29	Phosphorylation	DANEAIHSGPEENEG CCCCHHHCCCCCCCC	50.35	21659605
46	Phosphorylation	GQGKPEPSVGGDSKD CCCCCCCCCCCCCCC	31.56	19367708
51	Phosphorylation	EPSVGGDSKDREEAA CCCCCCCCCCHHHHH	39.47	19367708
66	Phosphorylation	AAENDPESPAEASDH HHHCCCCCHHHHHHC	34.49	27087446
71	Phosphorylation	PESPAEASDHGLPQP CCCHHHHHHCCCCCC	22.96	25619855
81	Phosphorylation	GLPQPPDTSTVSVIV CCCCCCCCCEEEEEE	31.88	25619855
82	Phosphorylation	LPQPPDTSTVSVIVK CCCCCCCCEEEEEEE	33.90	25619855
83	Phosphorylation	PQPPDTSTVSVIVKN CCCCCCCEEEEEEEC	20.92	25619855
85	Phosphorylation	PPDTSTVSVIVKNTV CCCCCEEEEEEECCC	13.25	25619855
91	Phosphorylation	VSVIVKNTVCPEQSE EEEEEECCCCHHHHH	20.12	25619855
97	Phosphorylation	NTVCPEQSESLTGDS CCCCHHHHHCCCCCC	27.73	25619855
99	Phosphorylation	VCPEQSESLTGDSGE CCHHHHHCCCCCCCC	36.16	27087446
101	Phosphorylation	PEQSESLTGDSGEEE HHHHHCCCCCCCCCC	48.50	27087446
104	Phosphorylation	SESLTGDSGEEETKA HHCCCCCCCCCCHHC	49.83	25521595
109	Phosphorylation	GDSGEEETKAGGITK CCCCCCCHHCCCCCC	29.49	22942356
115	Phosphorylation	ETKAGGITKEGPVGS CHHCCCCCCCCCCHH	26.73	26160508
142	Phosphorylation	SLSENPHSSAHASGN CCCCCCCCCCCCCCC	30.40	-
226	Phosphorylation	QGALKQESCSPHHSQ CCCCCCCCCCCHHHC	19.87	25159016
228	Phosphorylation	ALKQESCSPHHSQGL CCCCCCCCCHHHCCC	36.23	27087446
232	Phosphorylation	ESCSPHHSQGLTQRG CCCCCHHHCCCCCCC	23.94	25159016
236	Phosphorylation	PHHSQGLTQRGPGSS CHHHCCCCCCCCCCC	24.04	25777480
242	Phosphorylation	LTQRGPGSSPETAGI CCCCCCCCCCCCCCC	45.94	23684622
243	Phosphorylation	TQRGPGSSPETAGIP CCCCCCCCCCCCCCC	32.44	27087446
246	Phosphorylation	GPGSSPETAGIPASV CCCCCCCCCCCCCCC	33.30	23684622
252	Phosphorylation	ETAGIPASVSPPQVA CCCCCCCCCCCCCEE	20.13	27087446
254	Phosphorylation	AGIPASVSPPQVAGV CCCCCCCCCCCEEEE	28.50	27087446
262	Phosphorylation	PPQVAGVSFKQSPGH CCCEEEEECCCCCCC	26.30	25159016
266	Phosphorylation	AGVSFKQSPGHQSPP EEEECCCCCCCCCCC	33.18	27087446
271	Phosphorylation	KQSPGHQSPPASPVK CCCCCCCCCCCCCCC	27.46	25159016
275	Phosphorylation	GHQSPPASPVKAPSC CCCCCCCCCCCCCCC	35.68	25159016
345	Phosphorylation	SCGNITRTVTRVPSE CCCCEEEEEEECCCC	19.99	26745281
347	Phosphorylation	GNITRTVTRVPSEPD CCEEEEEEECCCCCC	25.90	26745281
351	Phosphorylation	RTVTRVPSEPDPPAP EEEEECCCCCCCCCC	59.93	25159016
368	Phosphorylation	EGAFLAETSFLKLSP CCCEEEECCCEEECC	21.12	26239621
369	Phosphorylation	GAFLAETSFLKLSPV CCEEEECCCEEECCC	21.78	26239621
374	Phosphorylation	ETSFLKLSPVTPTPE ECCCEEECCCCCCCC	18.75	25521595
377	Phosphorylation	FLKLSPVTPTPEGPK CEEECCCCCCCCCCE	25.48	26745281
379	Phosphorylation	KLSPVTPTPEGPKVV EECCCCCCCCCCEEE	25.30	23984901
387	Phosphorylation	PEGPKVVSVQLGDGT CCCCEEEEEECCCCC	13.72	-
394	Phosphorylation	SVQLGDGTRLKGTVL EEECCCCCEEECEEE	37.25	27149854
432	Phosphorylation	VLPGGNATSPKTMTK ECCCCCCCCCHHCCH	49.95	20469934
433	Phosphorylation	LPGGNATSPKTMTKS CCCCCCCCCHHCCHH	23.22	25521595
478	Phosphorylation	VMVQPSKSATGPGTA EEECCCCCCCCCCCC	35.09	25338131
495	Phosphorylation	SVISRTQSSLVEAFN CHHHHCHHHHHHHHH	25.65	24704852
496	Phosphorylation	VISRTQSSLVEAFNK HHHHCHHHHHHHHHH	26.98	27600695
514	Phosphorylation	SKNLLPAYRPNLSPP CCCCCCCCCCCCCCC	25.35	26643407
519	Phosphorylation	PAYRPNLSPPAEAGL CCCCCCCCCCCCCCC	35.16	26745281
721	Phosphorylation	LPNRCSFSAHQRTHK CCCCCCCCCCCHHHC	14.46	22802335
901	Phosphorylation	GAGGALLTPKTEPEE CCCCCCCCCCCCHHH	24.48	-
952	Acetylation	RRGELGNKGIKGGGG CCCCCCCCCCCCCCC	61.28	23806337
1008	Phosphorylation	RSFCSAPSLRRHVRV CCCCCCHHHHHCEEC	33.94	29176673
1058	Phosphorylation	GLPLGTQSSGRGGSL CCCCCCCCCCCCCCC	34.30	-
1061	Dimethylation	LGTQSSGRGGSLARG CCCCCCCCCCCCCCC	48.52	-
1061	Methylation	LGTQSSGRGGSLARG CCCCCCCCCCCCCCC	48.52	24129315
1067	Methylation	GRGGSLARGSGGRAQ CCCCCCCCCCCCCCC	45.14	18958559
1083	Phosphorylation	PGRKRRQSSDSCSEE CCCCCCCCCCCCCCC	34.01	25159016
1084	Phosphorylation	GRKRRQSSDSCSEEP CCCCCCCCCCCCCCC	25.79	25159016
1086	Phosphorylation	KRRQSSDSCSEEPDS CCCCCCCCCCCCCCC	22.84	25159016
1088	Phosphorylation	RQSSDSCSEEPDSTT CCCCCCCCCCCCCCC	49.28	25159016
1102	Methylation	TPPAKSLRGGPGSGG CCCCHHCCCCCCCCC	55.93	24129315
1107	Phosphorylation	SLRGGPGSGGHGPLR HCCCCCCCCCCCCCC	44.74	28066266
1117	Phosphorylation	HGPLRYRSSGSAEQS CCCCCCCCCCCCCCC	30.07	25777480
1118	Phosphorylation	GPLRYRSSGSAEQSL CCCCCCCCCCCCCCE	27.98	25777480
1120	Phosphorylation	LRYRSSGSAEQSLVG CCCCCCCCCCCCEEE	30.49	25266776
1124	Phosphorylation	SSGSAEQSLVGLRVD CCCCCCCCEEEEEEC	19.27	25777480
1134	Phosphorylation	GLRVDGGTQQCLDCG EEEECCCCCEECCCC	22.46	25619855
1146	Phosphorylation	DCGLCFASPGSLSRH CCCCEECCCCCHHHC	15.00	25619855
1149	Phosphorylation	LCFASPGSLSRHRFI CEECCCCCHHHCHHC	26.93	25619855
1151	Phosphorylation	FASPGSLSRHRFISH ECCCCCHHHCHHCCC	27.95	25619855
1184	Phosphorylation	EAAPPLRSDPEGGDS CCCCCCCCCCCCCCC	66.26	27087446
1191	Phosphorylation	SDPEGGDSPLPAPGD CCCCCCCCCCCCCCC	31.45	27087446
1201	Phosphorylation	PAPGDPLTCKVCGKS CCCCCCCEEEECCCC	18.70	26745281
1211	Phosphorylation	VCGKSCDSPLNLKTH ECCCCCCCCCCCCHH	35.30	26745281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN687_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN687_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN687_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN687_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.